A 15-Year-Old Girl Develops Malaise,headache,and Low-Grade Fever,followed by Pharyngitis and Cervical

Multiple Choice

A 15-year-old girl develops malaise,headache,and low-grade fever,followed by pharyngitis and cervical lymph node enlargement as a result of infectious mononucleosis caused by Epstein-Barr virus (EBV) .Her acute symptoms resolve within 2 weeks,and the fatigue improves within 3 months.All of the following are required for CD8⁺ cytotoxic T lymphocyte (CTL) recognition and killing of EBV-infected cells EXCEPT:

A) ( $\beta$ ₂) -Microglobulin
B) HLA-A,-B or -C
C) CD28
D) LFA-1 (leukocyte function-associated antigen-1)
E) TAP (transporter associated with antigen processing)