A 3-Year-Old Boy Is Taken to the Pediatrician Because of a Nosebleed

Multiple Choice

A 3-year-old boy is taken to the pediatrician because of a nosebleed (epistaxis) .He has a history of severe,recurrent sinopulmonary infection.Physical examination is remarkable for dry,red patches of skin (eczema) and multiple petechiae (tiny hemorrhagic spots) .Laboratory findings include thrombocytopenia and reduced IgM levels.The boy's maternal uncle died of bleeding complications after an emergency appendectomy.Which of the following represents a curative therapy currently available for this patient?

A) Passive immunization with gamma globulin
B) Bone marrow transplantation
C) Treatment with corticosteroids
D) Enzyme replacement
E) Gene therapy