Question 1

Purified protein from Bordetella pertussis is used in a(n)

Accepted Answer

A)  conjugated vaccine.
B)  subunit vaccine.
C)  nucleic acid vaccine.
D)  attenuated whole-agent vaccine.
E)  toxoid vaccine. B

Question 2

Table 18.1
Antibody Titer
 $$\begin{array} { | l | r | r | r | r | } 
\hline & \text { Day 1 } &  { \text { Day 7 } } & \text { Day 14 } & \text { Day 21 } \
\hline \text { Patient A } & 0 & 0 & 256 & 512 \
\hline \text { Patient B } & 128 & 256 & 512 & 1024 \
\hline \text { Patient C } & 0 & 0 & 0 & 0 \
\hline \text { Patient D } & 128 & 128 & 128 & 128 \
\hline
\end{array}$$
-In Table 18.1,who showed seroconversion during these observations?

Accepted Answer

A)  Patient A
B)  Patient B
C)  Patient C
D)  Patient D  A

Question 3

Which of the following is a test to determine the presence of soluble antigens in a patient's saliva?

Accepted Answer

A)  direct agglutination reaction
B)  passive agglutination reaction
C)  immunofluorescence
D)  neutralization reaction
E)  precipitation reaction E

Question 4

Blood typing tests are examples of hemagglutination reactions.

Accepted Answer

A) True 
 B)False

Question 5

Table 18.1
Antibody Titer
 $$\begin{array} { | l | r | r | r | r | } 
\hline & \text { Day 1 } &  { \text { Day 7 } } & \text { Day 14 } & \text { Day 21 } \
\hline \text { Patient A } & 0 & 0 & 256 & 512 \
\hline \text { Patient B } & 128 & 256 & 512 & 1024 \
\hline \text { Patient C } & 0 & 0 & 0 & 0 \
\hline \text { Patient D } & 128 & 128 & 128 & 128 \
\hline
\end{array}$$
-In Table 18.1,who probably has the disease?

Accepted Answer

A)  Patients A and B
B)  Patients B and C
C)  Patients A and C
D)  Patients C and D
E)  Patients A and D

Question 6

Which of the following is NOT an advantage of live attenuated vaccine agents?

Accepted Answer

A)  They elicit lifelong immunity.
B)  They stimulate by cell-mediated and humoral immune responses.
C)  They occasionally revert to virulent forms.
D)  They require few or no booster immunizations.
E)  The immune response generated by the vaccine closely mimics a real infection.

Question 7

Vaccines are preparations of organisms or fractions of organisms that are used to induce protective immune responses.

Accepted Answer

A) True 
 B)False

Question 8

A patient's serum,Mycobacterium,guinea pig complement,sheep red blood cells,and anti-sheep red blood cell antibodies are mixed in a test tube.What happens if the patient has antibodies to Mycobacterium?

Accepted Answer

A)  Bacteria fluoresce.
B)  Hemagglutination occurs.
C)  Hemagglutination-inhibition occurs.
D)  Hemolysis occurs.
E)  No hemolysis occurs.

Question 9

What type of vaccine is the live,weakened measles virus?

Accepted Answer

A)  conjugated vaccine
B)  subunit vaccine
C)  nucleic acid vaccine
D)  attenuated whole-agent vaccine
E)  toxoid vaccine

Question 10

If the table continued on to another week of testing,what is the one outcome below that you might NOT expect to see for Patient B at Day 28?

Accepted Answer

A)  a drop to zero antibody titer
B)  antibody titer continuing to rise
C)  antibody titer leveling off
D)  antibody titer starting to decrease slightly

Question 11

An injection of "naked" DNA into muscle cells to induce an immune response against the proteins encoded by the DNA is an example of a subunit vaccine.

Accepted Answer

A) True 
 B)False

Question 12

A reaction between antibody and particulate antigen is called a(n)

Accepted Answer

A)  agglutination reaction.
B)  complement fixation.
C)  immunofluorescence.
D)  neutralization reaction.
E)  precipitation reaction.

Question 13

A positive complement-fixation test is indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Accepted Answer

A) True 
 B)False

Question 14

When producing monoclonal antibodies,the use of ________ is critical after fusion to specifically allow only hybrid cells to grow.

Accepted Answer

A)  selective medium
B)  neutralizing antibodies
C)  enzymatically-labeled antibodies
D)  fluorescently-labeled antibodies
E)  complement

Question 15

The home pregnancy test kit is an example of a direct ELISA.

Accepted Answer

A) True 
 B)False

Question 16

Agglutination tests use particulate antigens while precipitation tests use soluble antigens.

Accepted Answer

A) True 
 B)False

Question 17

In an agglutination test,eight serial dilutions to determine antibody titer were set up.Tube #1 contained a 1:2 dilution;tube #2,a 1:4,etc.If tube #6 is the last tube showing agglutination,what is the antibody titer?

Accepted Answer

A)  6
B)  1:6
C)  64
D)  1:32
E)  32

Question 18

Figure 18.1
 
-Figure 18.1 is an illustration of a(n)

Accepted Answer

A)  negative indirect ELISA test.
B)  positive indirect ELISA test.
C)  complement fixation test.
D)  hemagglutination test.
E)  precipitation test.

Question 19

Which of the following is a pregnancy test used to find the fetal hormone HCG in a woman's urine using anti-HCG and latex spheres?

Accepted Answer

A)  direct agglutination reaction
B)  indirect agglutination reaction
C)  immunofluorescence
D)  neutralization reaction
E)  precipitation reaction

Question 20

Western blotting uses DNA probes to detect specific sequences in a mixture of proteins.

Accepted Answer

A) True 
 B)False

Exam 18: Practical Applications of Immunology

Purified protein from Bordetella pertussis is used in a(n)

Which of the following is a test to determine the presence of soluble antigens in a patient's saliva?

Blood typing tests are examples of hemagglutination reactions.

Which of the following is NOT an advantage of live attenuated vaccine agents?

Vaccines are preparations of organisms or fractions of organisms that are used to induce protective immune responses.

A patient's serum,Mycobacterium,guinea pig complement,sheep red blood cells,and anti-sheep red blood cell antibodies are mixed in a test tube.What happens if the patient has antibodies to Mycobacterium?

What type of vaccine is the live,weakened measles virus?

If the table continued on to another week of testing,what is the one outcome below that you might NOT expect to see for Patient B at Day 28?

An injection of "naked" DNA into muscle cells to induce an immune response against the proteins encoded by the DNA is an example of a subunit vaccine.

A reaction between antibody and particulate antigen is called a(n)

A positive complement-fixation test is indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

When producing monoclonal antibodies,the use of ________ is critical after fusion to specifically allow only hybrid cells to grow.

The home pregnancy test kit is an example of a direct ELISA.

Agglutination tests use particulate antigens while precipitation tests use soluble antigens.

In an agglutination test,eight serial dilutions to determine antibody titer were set up.Tube #1 contained a 1:2 dilution;tube #2,a 1:4,etc.If tube #6 is the last tube showing agglutination,what is the antibody titer?

Figure 18.1 -Figure 18.1 is an illustration of a(n)

Which of the following is a pregnancy test used to find the fetal hormone HCG in a woman's urine using anti-HCG and latex spheres?

Western blotting uses DNA probes to detect specific sequences in a mixture of proteins.