In Osteomyelitis, Bacteria Gain Access to the Subperiosteal Space in the Metaphysis

Multiple Choice

In osteomyelitis, bacteria gain access to the subperiosteal space in the metaphysis. What factor makes this route the easiest for bacteria to gain access to this area?

A) Cortex of the bone in this area is porous or mazelike.
B) Blood supply to the metaphysis is easily compromised.
C) Macrophages and lymphocytes have limited access to the subperiosteal space.
D) Bacteria usually spread down the medullary cavity of the bone.