Production of Adeno-Associated Virus (AAV)vectors Requires Several of the Proteins

Multiple Choice

Production of adeno-associated virus (AAV) vectors requires several of the proteins from adenovirus.What is the major advantage of expressing these proteins from plasmids rather than infecting the packaging cells with live adenovirus?

A) There will be no immune response against the infected cells.
B) There will be no adenovirus particles in the AAV virus preparations.
C) There will be no release of interferon from the infected cells.
D) The packaging cells will not become transformed.
E) The packaging cells will produce a higher amount of recombinant AAV particles.