Question 1

Which of the following is the recommended solution for the adverse effect of nausea following administration of a drug?

Accepted Answer

A)  Cease taking the drug.
B)  Go outside and get some fresh air.
C)  Take the drug with food or milk.
D)  Take the drug at bedtime.
E)  Seek medical attention. C

Question 2

A drug effect that is neither predictable nor dose related is called a

Accepted Answer

A)  therapeutic effect.
B)  toxic reaction.
C)  side effect.
D)  drug allergy.
E)  Both B and D are correct. D

Question 3

Which is safe to administer to a pregnant patient?

Accepted Answer

A)  Tetracycline
B)  NSAIDs
C)  Penicillin
D)  Benzodiazepines C

Question 4

A dose of a drug that kills 50% of experimental animals is termed

Accepted Answer

A)  ED50.
B)  minimally effective dose.
C)  LD50.
D)  therapeutic index.

Question 5

A dose-related reaction that produces undesirable effects caused by the action on nontarget organs is called a

Accepted Answer

A)  therapeutic effect.
B)  toxic reaction.
C)  side effect.
D)  drug allergy.

Question 6

Type _____ hypersensitivity is mediated by IgE antibodies.

Accepted Answer

A)  I
B)  II
C)  III
D)  IV

Question 7

Immune-complex disease reactions are aggregations of antibodies and

Accepted Answer

A)  T lymphocyte cells.
B)  B lymphocyte cells.
C)  antigens.
D)  plasma cells.

Question 8

Which hypersensitivity reaction causes antibody-antigen (immune complex)deposition?

Accepted Answer

A)  Type I
B)  Type II
C)  Type III
D)  Type IV

Question 9

Which hypersensitivity reaction is termed delayed-type hypersensitivity and is mediated by sensitized T lymphocytes and macrophages?

Accepted Answer

A)  Type I
B)  Type II
C)  Type III
D)  Type IV

Question 10

An acute,life-threatening allergic reaction characterized by hypotension,bronchospasm,laryngeal edema,and cardiac arrhythmias is what type of hypersensitivity?

Accepted Answer

A)  Type I
B)  Type II
C)  Type III
D)  Type IV

Question 11

Which will block the action of histamine during an allergic reaction?

Accepted Answer

A)  Macrolide
B)  Epinephrine
C)  Anticonvulsants
D)  Benzodiazepines

Question 12

Although drug A and drug B have the same ED₅₀,drug B has a wider therapeutic index (TI);therefore,drug A has a greater LD₅₀ than drug B.

Accepted Answer

A)  Both statements are true.
B)  Both statements are false.
C)  The first statement is true,the second is false.
D)  The first statement is false,the second is true.

Question 13

What should the dental hygienist do first if a patient reports a suspected adverse drug effect?

Accepted Answer

A)  Administer epinephrine.
B)  Determine what drugs the patient is taking.
C)  Have that patient drink a sugary liquid such as apple juice.
D)  Call 9-1-1.
E)  Drive the patient to the nearest hospital emergency room.

Question 14

A genetically related abnormal drug response is called a(n)

Accepted Answer

A)  toxic reaction.
B)  idiosyncratic reaction.
C)  side effect.
D)  drug allergy.

Question 15

The greatest risk to the fetus from exposure to drugs occurs

Accepted Answer

A)  just before birth.
B)  during the third trimester.
C)  during the second trimester.
D)  before pregnancy status is known.

Question 16

The greater the therapeutic index is,the greater the toxicity will be.

Accepted Answer

A) True 
 B)False

Question 17

Which is least likely to be a true allergic reaction?

Accepted Answer

A)  Urticaria
B)  Rash
C)  Anaphylaxis
D)  Dyspepsia

Question 18

Tetracycline,nonsteroidal antiinflammatory drugs (NSAIDs),and the benzodiazepines are safe to administer to a pregnant patient.

Accepted Answer

A) True 
 B)False

Question 19

The following choices refer to adverse reactions involving exaggerated effects on target tissues except

Accepted Answer

A)  overreaction of a sensitive patient.
B)  administration of too large a dose.
C)  caused by a nontherapeutic action of a drug.
D)  possibly resulting from liver or kidney disease.

Question 20

Drug allergy and a side effect are two examples of dose-related responses.

Accepted Answer

A) True 
 B)False

Exam 3: Adverse Reactions

Which of the following is the recommended solution for the adverse effect of nausea following administration of a drug?

A drug effect that is neither predictable nor dose related is called a

Which is safe to administer to a pregnant patient?

A dose of a drug that kills 50% of experimental animals is termed

A dose-related reaction that produces undesirable effects caused by the action on nontarget organs is called a

Type _____ hypersensitivity is mediated by IgE antibodies.

Immune-complex disease reactions are aggregations of antibodies and

Which hypersensitivity reaction causes antibody-antigen (immune complex) deposition?

Which hypersensitivity reaction is termed delayed-type hypersensitivity and is mediated by sensitized T lymphocytes and macrophages?

An acute,life-threatening allergic reaction characterized by hypotension,bronchospasm,laryngeal edema,and cardiac arrhythmias is what type of hypersensitivity?

Which will block the action of histamine during an allergic reaction?

Although drug A and drug B have the same ED₅₀,drug B has a wider therapeutic index (TI) ;therefore,drug A has a greater LD₅₀ than drug B.

What should the dental hygienist do first if a patient reports a suspected adverse drug effect?

A genetically related abnormal drug response is called a(n)

The greatest risk to the fetus from exposure to drugs occurs

The greater the therapeutic index is,the greater the toxicity will be.

Which is least likely to be a true allergic reaction?

Tetracycline,nonsteroidal antiinflammatory drugs (NSAIDs),and the benzodiazepines are safe to administer to a pregnant patient.

The following choices refer to adverse reactions involving exaggerated effects on target tissues except

Drug allergy and a side effect are two examples of dose-related responses.