Multiple Choice
GTPases serve in many signal transduction pathways and the presence of GTP or GDP dictates whether the pathway is on or off,respectively.Which of the following statements is true regarding guanine nucleotide exchange factors (GEF) and their role in these signaling pathways?
A) They hydrolyze GTP into GDP and Pᵢ.
B) They decrease the GTPase activity of the G-protein.
C) They catalyze the dissociation of GDP on the G-protein to therefore promote the replacement of GTP.
D) none of the above
Correct Answer:
Verified
Correct Answer:
Verified
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