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The Partition Coefficient K,the Equilibrium Constant for Partitioning Between Oil

Question 44

Multiple Choice

The partition coefficient K,the equilibrium constant for partitioning between oil and water,for butyric acid is about 10-²,and for 1,4-butanediol it is about 10-⁴.You add liposomes containing only water to a solution with an initial concentration of 1 mM butyric acid and 100 mM 1,4-butanediol outside the liposomes.What is the relative rate of diffusion of the two substances into the liposome interior?


A) Butyric acid diffuses into the liposome 100-fold faster than butanediol.
B) The two diffuse into the liposome at equal rates.
C) Butanediol diffuses into the liposome 100-fold faster than butanediol.
D) Not enough information is provided to permit an answer.

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