Why Is Transcriptional Control of Gene Expression More Difficult in Eukaryotes

Multiple Choice

Why is transcriptional control of gene expression more difficult in eukaryotes than in prokaryotes?
1) Genes are sequestered in the nucleus.
2) Eukaryotic cells need fairly elaborate internal signaling systems to control the transcription of DNA.
3) Environmental cues may have to pass through layers of cells in order to have an impact on the transcription of genes in a particular tissue.

A) 1
B) 2
C) 3
D) 1 and 2
E) All of these are correct.