Which Factors) Produces) the Greatest Risk for Cleft Lip

Multiple Choice

Which factors) produces) the greatest risk for cleft lip?

A) Carrying the rare polymorphism of the TGFA gene
B) Having a family history with two affected first-degree relatives with cleft lip
C) Heavy maternal smoking plus carrying the high-risk allele of TGF
D) Having a family history with one individual with cleft lip
E) Heavy maternal smoking