Data Shown in the Two Graphs Below Are from Experiments

Short Answer

Data shown in the two graphs below are from experiments carried out on pyruvate dehydrogenase (PDH), the enzyme that catalyzes the conversion of pyruvate to acetyl CoA and carbon dioxide. In the experiments, extracts of mitochondria were incubated for 6 minutes with high concentrations of ATP labeled with phosphorus-32.At various times, samples were removed and tested for PDH activity and incorporation of phosphorus-32 (³²P) label into PDH.The results shown in the graphs suggest that PDH is regulated via a mechanism involving _______ of the PDH protein.