Which Characterizes a Right Shift in the O₂-Binding/dissociation Curve of Hemoglobin

Multiple Choice

Which characterizes a right shift in the O₂-binding/dissociation curve of hemoglobin?

A) Hemoglobin has increased affinity for O₂.
B) A higher PO₂ is needed to achieve the same O₂ saturation.
C) Hemoglobin has less difficulty binding O₂.
D) It can be caused by increases in pH.
E) It is harder for hemoglobin to release its bound O₂.