Multiple Choice
Ultra-rapid metabolizers of drugs may have:
A) To have dosages of drugs adjusted downward to prevent drug accumulation
B) Active drug rapidly metabolized into inactive metabolites, leading to potential therapeutic failure
C) Increased elimination of active, nonmetabolized drug
D) Slowed metabolism of a prodrug into an active drug, leading to an accumulation of prodrug
Correct Answer:

Verified
Correct Answer:
Verified
Q1: A genetic variation in how the metabolite
Q3: Genetic polymorphisms account for differences in metabolism,
Q4: Carbamazepine has a Black Box Warning recommending
Q5: Warfarin resistance may be seen in patients
Q6: A provider may consider testing for CYP2D6
Q7: Patients who have a poor metabolism phenotype
Q8: Rifampin is a nonspecific CYP450 inducer that
Q9: Up to 21% of Asians are ultra-rapid
Q10: Inhibition of P-glycoprotein by a drug such
Q11: Pharmacogenetic testing is required by the U.S.