How Does Primary Protein Structure Affect the Function of Protein

Multiple Choice

How does primary protein structure affect the function of protein enzymes?

A) Substrates interact with R-groups at the enzyme's active site.
B) Substrates interact with R-groups at the enzyme's external surface.
C) Substrates interact with hydrophobic R-groups at any region of the enzyme.
D) Substrates permanently bind to R-groups at the enzyme's active site.