Question 1

A child has been diagnosed with Fragile X syndrome.The nurse would explain that this child is at risk for which other disorders?

Accepted Answer

A)  Autism
B)  Hyperactivity
C)  Mitral valve prolapse
D)  Learning disabilities
E)  Huntington disease A,B,C,D

Question 2

A client is diagnosed with a single-gene disorder on a non-sex chromosome.How would the nurse describe this disorder?

Accepted Answer

A)  X-linked
B)  Y-linked
C)  Monogenic
D)  Dominant
E)  Autosomal C,E

Question 3

The mother of a client with cystic fibrosis (CF)says,"I don't understand why my son is sick so often when some of the other children in our CF support group are hardly ever sick." How should the nurse respond?

Accepted Answer

A)  "We should probably test your son's immune system."
B)  "There are many different type of CF,and they affect different people differently."
C)  "Are you certain you have been following his medication schedule exactly?"
D)  "Children have different levels of disease because they have differing amounts of dysfunction in the gene that causes CF." D

Question 4

A client being treated for cancer is offended because she overheard a nurse say that the client had "wild-type genes." How should the nurse respond to calm this client?

Accepted Answer

A)  "Wild-type genes are a type of gene that is stronger than normal."
B)  "The nurse was describing your resilience in fighting your illness so effectively."
C)  "The nurse was discussing a type of gene we are seeing in clients treated for cancer."
D)  "Wild-type genes are those that are normal and have not been affected by any mutation."

Question 5

The nurse is reviewing an obstetric client's history and physical assessment.Which finding is most likely to alert the nurse to the possibility of a genetic disorder in the infant?

Accepted Answer

A)  Family history of genetic disorders
B)  Infant's large size for gestational age
C)  Low serum glucose in mother on initial screening
D)  History of smoking in mother and father

Question 6

A male infant is diagnosed with a disorder of mitochondrial inheritance.What should the nurse consider when developing a teaching plan about this disorder for the parents?

Accepted Answer

A)  This disorder will affect the baby's immunity.
B)  It is very rare for a male child to be affected.
C)  The child inherited this disorder from the mother.
D)  This baby will likely not live past a few weeks.

Question 7

A couple has delivered an infant with a serious genetic disorder.Which nursing diagnoses would likely apply to this family?

Accepted Answer

A)  Altered Family Processes
B)  Anticipatory Grieving
C)  Anxiety
D)  Ineffective Denial
E)  Ineffective Management: Therapeutic Family Regimen

Question 8

A client is diagnosed with a disorder that has an autosomal dominant inheritance pattern.A review of the client's family history and pedigree does not reveal any ancestors with the disorder.How should the nurse interpret this finding?

Accepted Answer

A)  Errors have been made in the documentation of the client's history.
B)  Some ancestors experienced effects that were so minor they were not recognized.
C)  A de novo mutation has occurred.
D)  The client's genetic testing should be repeated.

Question 9

A nurse is providing preconception counseling to a healthy woman and her husband,who has hemophilia A.They are very concerned about passing the disorder on to their children.What should the nurse consider before addressing this concern?

Accepted Answer

A)  Hemophilia A is diagnosed in men and women in equal numbers.
B)  The daughters produced by this union will be carriers of the disorder.
C)  The sons of this union will have hemophilia A.
D)  The daughters of this union will have a 50% chance of passing hemophilia A on to their daughters.
E)  None of the children of this union will manifest hemophilia A.

Question 10

A client has been diagnosed with an autosomal recessive disorder that developed in middle adulthood.No other people in his family have manifested the disorder.The client asks the nurse why he is affected and if his children are at risk.What would the nurse consider when formulating a reply?

Accepted Answer

A)  The client's mother is a carrier of the disorder.
B)  The odds are high that at least one of the client's four younger siblings either is a carrier for the disease or will develop it in later life.
C)  The client's father is a carrier for the disorder.
D)  Because the disorder is recessive,the client's children have a 25% chance of having inherited it.
E)  All of the client's children are at least carriers of the disorder.

Question 11

The evaluation of a family pedigree reveals numerous cases of an autosomal dominant disorder.The client does not have the disorder.What does the nurse teach the client about her children's chances of having the disorder?

Accepted Answer

A)  "Your children have a 50% chance of developing the disorder."
B)  "If your children's father does not have the disease,they will not have the disease."
C)  "Your children cannot develop the disease."
D)  "These disorders tend to skip a generation,so there is a good chance your children will develop it." 5.

Question 12

A client has been diagnosed with a rare autosomal recessive disorder.Which finding is the nurse most likely to assess in the client's pedigree?

Accepted Answer

A)  Deaths from other autosomal recessive disorders
B)  Many families units with only one child
C)  Marriages between first cousins
D)  An unusual number of adopted children

Question 13

A teenager is diagnosed with a disorder of mitochondrial inheritance.What assessment findings would the nurse expect to find in this client's history?

Accepted Answer

A)  Hearing loss
B)  Loss of ability to taste
C)  Frequent nosebleeds
D)  Exercise intolerance
E)  Generalized fatigue

Question 14

A man who has a Y-linked disorder has married a healthy woman.The couple is concerned about passing the man's disorder to their children.What should the nurse consider before responding to this concern?

Accepted Answer

A)  Only the female children will be affected.
B)  Female fetuses with this genotype do not survive to birth.
C)  Only male children will be affected.
D)  The chance the father will pass the disease on to male children is 1 in 2.

Exam 7: Mendelian Inheritance