Immune Responses to Tumors Have Been Studied Extensively in Mice

Multiple Choice

Immune responses to tumors have been studied extensively in mice, using transplantable tumors injected into syngeneic mice. The basis for many of these studies is the assumption that the process of tumorigenesis generates mutations in genes encoding self-antigens that would allow the immune system to see these mutant proteins as 'foreign'. In this scenario, the dominant immune response targeting the tumor cells would be mediated by:

A) Antibodies
B) CD4 T_H1 cells
C) CD8 T cells
D) NK cells
E) FcR+ phagocytic cells