While CD28 Co-Stimulation Is Important for the Initial Activation of Naive

Multiple Choice

While CD28 co-stimulation is important for the initial activation of naive T cells, other co-stimulatory molecules function at later stages of the T cell response. Several of these other co-stimulatory molecules are members of the TNF-receptor family, and function by activating the transcription factor, NF $\kappa$ B. Therefore, stimulation of these co-stimulatory TNF-receptors on activated T cells is likely to:

A) Induce programmed cell death in the T cell
B) Enhance T cell survival
C) Increase T cell proliferation
D) Promote T cell migration into tissues
E) Inhibit T cell activation and differentiation