Genetically Inherited Immunodeficiency Diseases Can Result from Defects in Nearly

Multiple Choice

Genetically inherited immunodeficiency diseases can result from defects in nearly any component of the immune response. The most severe forms of immunodeficiency occur when T cells are absent or non-functional. An individual with normal B cells, but an absence of T cells might have a defect in:

A) RAG-1 or RAG-2 recombinase proteins
B) Terminal deoxynucleotidyl transferase (TdT)
C) Hematopoietic stem cells
D) Bone marrow stromal cells
E) Thymic stromal cells