If One Swapped the Regulatory Elements of the TCR $\alpha$ And TCR

Essay

If one swapped the regulatory elements of the TCR $\alpha$ and TCR $\beta$ loci, so that rearrangement and expression of the TCR $\alpha$ locus occurred first, in double-negative thymocytes, and TCR $\beta$ rearrangement and expression were delayed until the double-positive stage, would T cell development proceed normally to generate mature T cells? Why or why not?