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RIG-I Like Receptors (RLRs) Such as RIG-I, MDA-5, and STING

Question 11

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RIG-I like receptors (RLRs) such as RIG-I, MDA-5, and STING are cytoplasmic nucleic acid sensors. Give two examples of how such innate sensors distinguish between the RNA/DNA of the host from that of an infecting pathogen.

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1. Unique structure: RIG-I recognizes si...

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