In Recent Years, Several New Vaccines Have Been Developed That

Multiple Choice

In recent years, several new vaccines have been developed that are made from purified viral surface proteins, rather than intact or live viruses. They are referred to as subunit vaccines. In order to generate a protective adaptive immune response to a subunit vaccine, the viral protein(s) must be mixed with an adjuvant. The adjuvant functions to:

A) Mimic the process of normal virus entry by binding to the host receptor and inducing receptor-mediated endocytosis
B) Induce vascular permeability to promote the accumulation of fluid and serum proteins at the vaccine injection site
C) Induce the production of chemotactic proteins that recruit neutrophils and then monocytes to the site of vaccine injection
D) Stimulate dendritic cells to up-regulate co-stimulatory molecules and migrate to the regional lymph node
E) Promote the activation of the complement cascade to induce complement deposition on the viral subunit proteins