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Two Strains of Mice Were Infected with 5 ×\times 104 PFU of Influenza a Virus, and the Survival Data

Question 21

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Two strains of mice were infected with 5 ×\times 104 PFU of Influenza A virus, and the survival data shown in Figure were obtained.  Two strains of mice were infected with 5  \times  10<sup>4</sup> PFU of Influenza A virus, and the survival data shown in Figure were obtained.    Next, both strains were infected again with Influenza A, and levels of type I interferons (IFN- \alpha  and IFN- \beta )  were measured and found to be similar between the two strains. Likewise, cells from both strains expressed similar levels of the IFN- \alpha / \beta receptor (IFNAR) . Which of the following proteins might be more highly expressed in strain B than in strain A following Influenza A infection? A)  MHC class I B)  Mx-1 C)  TLR4 D)  Complement C3 E)  ICAM-1
Next, both strains were infected again with Influenza A, and levels of type I interferons (IFN- α\alpha and IFN- β\beta ) were measured and found to be similar between the two strains. Likewise, cells from both strains expressed similar levels of the IFN- α\alpha / β\beta receptor (IFNAR) . Which of the following proteins might be more highly expressed in strain B than in strain A following Influenza A infection?


A) MHC class I
B) Mx-1
C) TLR4
D) Complement C3
E) ICAM-1

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