Many Different Viruses Encode Proteins That Function to Down-Regulate MHC

Multiple Choice

Many different viruses encode proteins that function to down-regulate MHC class I expression on host cells following infection with the virus. This immune evasion mechanism allows the virus to hide from CD8 T lymphocytes that normally detect virus-infected cells by using their T cell antigen receptor to recognize viral peptides bound to MHC class I proteins on the surface of the infected cell. To counteract this immune evasion strategy, NK cells have:

A) Activating receptors that recognize MHC class I proteins
B) A mechanism to secrete antiviral peptides
C) Inhibitory receptors that recognize viral capsid proteins
D) Activating receptors that recognize viral capsid proteins
E) Inhibitory receptors that recognize MHC class I proteins