True/False
Neutrophils regulate the production of active cathelicidins (a class of antimicrobial peptides) by segregating the inactive propeptide from the processing enzyme that cleaves and activates it in two different types of cytoplasmic granules. These two types of granules are induced to fuse with phagosomes after ingestion of microbes, bringing the processing enzyme and the propeptide together.
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Correct Answer:
Verified
Q1: The production of antimicrobial peptides is one
Q2: Epithelial surfaces provide the first line of
Q3: The C3 convertase of the alternative complement
Q5: Opsonization of pathogens by both antibodies and
Q6: The importance of complement activation as an
Q7: Streptococcus pneumoniae is a Gram-positive bacterium that
Q8: Mannose binding lectins (MBL) and ficolins are
Q9: Although the complement cascade can be initiated
Q10: The C3 convertase amplifies the process of
Q11: Although homozygous deficiencies in complement regulatory proteins