Cells from Advanced Malignant Tumors Often Have Very Abnormal Chromosomes

Multiple Choice

Cells from advanced malignant tumors often have very abnormal chromosomes as well as an abnormal number of chromosomes. What might explain the association between malignant tumors and chromosomal abnormalities?

A) Cancer cells are no longer density dependent.
B) Cancer cells are no longer anchorage dependent.
C) Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.
D) Chromosomally abnormal cells still have normal metabolism.
E) Transformation introduces new chromosomes into cells.