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E Coli RNA Polymerase (RNAP) Has No 3' to 5

Question 15

Multiple Choice

E. coli RNA polymerase (RNAP) has no 3' to 5' exonuclease activity. Which statement BEST explains why this is not a required activity for this enzyme?


A) RNAP makes fewer errors in NTP addition, so this activity is unnecessary.
B) RNAP does not need to degrade nucleic acids ahead of the transcription bubble.
C) Errors in transcription will have no impact on the function of the RNA product.
D) Multiple RNA products are created and turnover rapidly, so errors have less impact.
E) None of the statements explains why this is not a required activity.

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