Exam 4: Proteins: Three-Dimensional Structure and Function

Proteins segments which fold first can promote the folding of other sections of the protein into the native conformation by a process known as

Water can easily penetrate and even pass through the interior of a folded protein.

Homologous proteins can be identified not only by sequencing, but also by comparing similarities in tertiary structure.

Protein subunits in a multisubunit protein are held to each other primarily by

Match each level of organization with a description. A) Overall shape of a protein B) Repeated pattern of folding C) Multiple subunits are present D) Specific order of amino acids -Tertiary structure

The conformation of the backbone of a polypeptide is described completely by the angles) of rotation about which bonds)?

A helical wheel can be used to show

Which statement is not true about the peptide bond?

Match each level of organization with a description. A) Overall shape of a protein B) Repeated pattern of folding C) Multiple subunits are present D) Specific order of amino acids -Quaternary structure

Match the protein organization most associated with the terms) listed below: A) Tertiary B) Secondary C) Primary D) Quaternary -Subunits

In oligomeric proteins all the subunits are always identical.

In peptide bonds, the bonds between

The Bohr effect describes the effect of pH on hemoglobinʹs ability to bind oxygen. Oxygen binds more tightly at low pH and less tightly at higher pH values.

For each term select the description that best describes its contribution to the structure of collagen. A) Has $\mathrm{H}$ bonds which help stabilize the protein B) Makes the protein rigid C) Required for hydroxylation D) Forms covalent cross links E) Allows tightly wound helix formation -Hydroxyproline

In addition to self assembly, some proteins fold with the help of

The amount of energy required to denature a protein is often small.

Which statement is not true about an α-helix?

received a Nobel Prize in 1964 for determining the structure of vitamin B₁₂. He/she also solved the structure of penicillin in 1947 and developed many techniques used in the study of large proteins.

For each term select the description that best describes its contribution to the structure of collagen. A) Has $\mathrm{H}$ bonds which help stabilize the protein B) Makes the protein rigid C) Required for hydroxylation D) Forms covalent cross links E) Allows tightly wound helix formation -Glycine

Cooperative binding and allosterism of hemoglobin allow oxygen to be unloaded at low partial pressures of oxygen in the tissues.