Question 1

Which agency enforces polices of the Public Health Service?

Accepted Answer

A)  U.S. Department of Agriculture 
B)  Food and Drug Administration 
C)  Office of Laboratory Animal Welfare 
D)  National Research Council 
A)  U.S. Department of Agriculture 
B)  Food and Drug Administration 
C)  Office of Laboratory Animal Welfare 
D)  National Research Council

Question 2

What is a limitation of informed consent?

Accepted Answer

A)  It precludes the use of blind-studies. 
B)  It does not allow children and mental incapable adults to participate in research studies. 
C)  It may lead to a breach of patient confidentiality. 
D)  Certain subject groups may not be able to directly give informed consent. 
A)  It precludes the use of blind-studies. 
B)  It does not allow children and mental incapable adults to participate in research studies. 
C)  It may lead to a breach of patient confidentiality. 
D)  Certain subject groups may not be able to directly give informed consent.

Question 3

What is a limitation of using human subjects for psychopharmacology research?

Accepted Answer

A)  Invasive measures are not possible. 
B)  The research is not cost effective. 
C)  The research is too time consuming. 
D)  Human populations are typically homogenous. 
A)  Invasive measures are not possible. 
B)  The research is not cost effective. 
C)  The research is too time consuming. 
D)  Human populations are typically homogenous.

Question 4

Dr. Ma designs a study to test the effects of the novel anti-inflammatory drug InflaMED on a model of inflammation in laboratory rats. What does Dr. Ma first need to do?

Accepted Answer

A)  Perform preliminary experiments on the rats before getting IACUC approval. 
B)  Submit a proposal to IACUC before starting any animal experiments. 
C)  Perform safety experiments on isolated cells or tissue before getting IACUC approval. 
D)  Ensure human tolerance for InflaMED before getting IACUC approval. 
A)  Perform preliminary experiments on the rats before getting IACUC approval. 
B)  Submit a proposal to IACUC before starting any animal experiments. 
C)  Perform safety experiments on isolated cells or tissue before getting IACUC approval. 
D)  Ensure human tolerance for InflaMED before getting IACUC approval.

Question 5

Which is an example of a clinical trial that is currently in Phase II?

Accepted Answer

A)  Study participants are given a low dose of Drug X to ensure its safety. 
B)  Study participants are followed for at least one year to determine the safety and efficacy of the drug. 
C)  Study participants from a more diverse background are given a large dose of Drug X for a long duration to test its safety and efficacy. 
D)  Study participants are given a larger dose of Drug X to determine its efficacy. 
A)  Study participants are given a low dose of Drug X to ensure its safety. 
B)  Study participants are followed for at least one year to determine the safety and efficacy of the drug. 
C)  Study participants from a more diverse background are given a large dose of Drug X for a long duration to test its safety and efficacy. 
D)  Study participants are given a larger dose of Drug X to determine its efficacy.

Question 6

If drug A has an ED50 value of 12.0 mg/kg, and drug B has an ED50 value of 4.0 mg/kg, what can we say about the potencies of these drugs?

Accepted Answer

A)  Drug A is three times more potent than drug B. 
B)  Drug A is eight times more potent than drug B. 
C)  Drug B is three times more potent than drug A. 
D)  Drug B is eight times more potent than drug A. 
A)  Drug A is three times more potent than drug B. 
B)  Drug A is eight times more potent than drug B. 
C)  Drug B is three times more potent than drug A. 
D)  Drug B is eight times more potent than drug A.

Question 7

Modern animal rights activities largely began after publication of philosopher Peter Singer's, book ____.

Accepted Answer

A)  End the Carnage 
B)  What Gives Us the Right? 
C)  Animal Liberation 
D)  We Are Animals Too 
A)  End the Carnage 
B)  What Gives Us the Right? 
C)  Animal Liberation 
D)  We Are Animals Too

Question 8

The study of how drugs pass through the body is referred to as ____.

Accepted Answer

A)  pharmacogenetics 
B)  pharmacodynamics 
C)  pharmacovigilence 
D)  pharmacokinetics 
A)  pharmacogenetics 
B)  pharmacodynamics 
C)  pharmacovigilence 
D)  pharmacokinetics

Question 9

The ability to extend findings beyond experimental conditions is referred to as ____.

Accepted Answer

A)  external validity 
B)  internal validity 
C)  construct validity 
D)  face validity 
A)  external validity 
B)  internal validity 
C)  construct validity 
D)  face validity

Question 10

Dr. Engle is a toxicologist at the pharmaceutical company Pharma Giant. He wants to calculate a conservative value for his therapeutic index. Which formula should he use?

Accepted Answer

A)  LD1/ED99 
B)  ED99/LD1 
C)  LD50/ED50 
D)  ED50/LD50 
A)  LD1/ED99 
B)  ED99/LD1 
C)  LD50/ED50 
D)  ED50/LD50

Question 11

Cadence drinks caffeine every morning to help her wake up. Cadence's use of caffeine is considered instrumental because she ____.

Accepted Answer

A)  uses caffeine entirely to experience its effects 
B)  is addicted to caffeine 
C)  is addressing a specific purpose 
D)  does not use caffeine for a medical purpose 
A)  uses caffeine entirely to experience its effects 
B)  is addicted to caffeine 
C)  is addressing a specific purpose 
D)  does not use caffeine for a medical purpose

Question 12

The adequacy of controlling variables that may obscure study results and reliability is referred to as ____.

Accepted Answer

A)  external validity 
B)  face validity 
C)  predictive validity 
D)  internal validity 
A)  external validity 
B)  face validity 
C)  predictive validity 
D)  internal validity

Question 13

Institutional Animal Care and Use Committee (IACUC) makes ethical judgments according to its "3 R's": ____.

Accepted Answer

A)  replacement, reduction, and respect 
B)  respect, replacement, and refinement 
C)  respect, reduction, and refinement 
D)  replacement, reduction, and refinement 
A)  replacement, reduction, and respect 
B)  respect, replacement, and refinement 
C)  respect, reduction, and refinement 
D)  replacement, reduction, and refinement

Question 14

____ weigh the value of potential research discoveries against the potential pain and distress experienced by research animals.

Accepted Answer

A)  Therapeutic indexes 
B)  Informed consents 
C)  Cost-benefit ratios 
D)  Ethical cost assessments 
A)  Therapeutic indexes 
B)  Informed consents 
C)  Cost-benefit ratios 
D)  Ethical cost assessments

Question 15

In the United States, which governmental agency oversees the regulation of human research?

Accepted Answer

A)  National Institutes of Health 
B)  Food and Drug Administration 
C)  Center for Disease Control 
D)  Office of Protection from Research Risks 
A)  National Institutes of Health 
B)  Food and Drug Administration 
C)  Center for Disease Control 
D)  Office of Protection from Research Risks

Question 16

For the IACUC, the 3 R's address the necessity of using animals. The first "R" replacement refers to: ____.

Accepted Answer

A)  finding alternatives to animal research 
B)  minimizing the number of animals used 
C)  reducing costs associated with animal research 
D)  minimizing the pain and distress of animals 
A)  finding alternatives to animal research 
B)  minimizing the number of animals used 
C)  reducing costs associated with animal research 
D)  minimizing the pain and distress of animals

Question 17

Psychopharmacology is the study of how drugs affect mood, perception, thinking, or ____.

Accepted Answer

A)  motor control 
B)  behavior 
C)  immune function 
D)  biological development 
A)  motor control 
B)  behavior 
C)  immune function 
D)  biological development

Question 18

Medical advances rely on animal research for three major reasons: ____.

Accepted Answer

A)  lack of feasible alternatives; high predictive value; diversity of animal populations 
B)  lack of feasible alternatives; diversity of animal populations; drug assessment in controlled environment 
C)  high predictive value; lack of feasible alternatives; drug assessment in controlled environment 
D)  diversity of animal populations; high predictive value; drug assessment in controlled environment 
A)  lack of feasible alternatives; high predictive value; diversity of animal populations 
B)  lack of feasible alternatives; diversity of animal populations; drug assessment in controlled environment 
C)  high predictive value; lack of feasible alternatives; drug assessment in controlled environment 
D)  diversity of animal populations; high predictive value; drug assessment in controlled environment

Question 19

What is the purpose of performing an open-label study?

Accepted Answer

A)  Withholding treatment may be unethical. 
B)  Feedback from study participants is important. 
C)  Researchers must know which patients receive which treatment. 
D)  Informed consent is only possible with open-label studies. 
A)  Withholding treatment may be unethical. 
B)  Feedback from study participants is important. 
C)  Researchers must know which patients receive which treatment. 
D)  Informed consent is only possible with open-label studies.

Question 20

When a model appears similar to a disorder, this is referred to as ____.

Accepted Answer

A)  construct validity 
B)  predictive validity 
C)  internal validity 
D)  face validity 
A)  construct validity 
B)  predictive validity 
C)  internal validity 
D)  face validity

Which agency enforces polices of the Public Health Service?

What is a limitation of informed consent?

What is a limitation of using human subjects for psychopharmacology research?

Dr. Ma designs a study to test the effects of the novel anti-inflammatory drug InflaMED on a model of inflammation in laboratory rats. What does Dr. Ma first need to do?

Which is an example of a clinical trial that is currently in Phase II?

If drug A has an ED₅₀ value of 12.0 mg/kg, and drug B has an ED₅₀ value of 4.0 mg/kg, what can we say about the potencies of these drugs?

Modern animal rights activities largely began after publication of philosopher Peter Singer's, book ____.

The study of how drugs pass through the body is referred to as ____.

The ability to extend findings beyond experimental conditions is referred to as ____.

Dr. Engle is a toxicologist at the pharmaceutical company Pharma Giant. He wants to calculate a conservative value for his therapeutic index. Which formula should he use?

Cadence drinks caffeine every morning to help her wake up. Cadence's use of caffeine is considered instrumental because she ____.

The adequacy of controlling variables that may obscure study results and reliability is referred to as ____.

Institutional Animal Care and Use Committee (IACUC) makes ethical judgments according to its "3 R's": ____.

____ weigh the value of potential research discoveries against the potential pain and distress experienced by research animals.

In the United States, which governmental agency oversees the regulation of human research?

For the IACUC, the 3 R's address the necessity of using animals. The first "R" replacement refers to: ____.

Psychopharmacology is the study of how drugs affect mood, perception, thinking, or ____.

Medical advances rely on animal research for three major reasons: ____.

What is the purpose of performing an open-label study?

When a model appears similar to a disorder, this is referred to as ____.

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

Ghb, Inhalants, and Anesthetics

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters

Exam 1: Introduction to Psychopharmacology

Which agency enforces polices of the Public Health Service?

What is a limitation of informed consent?

What is a limitation of using human subjects for psychopharmacology research?

Dr. Ma designs a study to test the effects of the novel anti-inflammatory drug InflaMED on a model of inflammation in laboratory rats. What does Dr. Ma first need to do?

Which is an example of a clinical trial that is currently in Phase II?

If drug A has an ED50 value of 12.0 mg/kg, and drug B has an ED50 value of 4.0 mg/kg, what can we say about the potencies of these drugs?

Modern animal rights activities largely began after publication of philosopher Peter Singer's, book ____.

The study of how drugs pass through the body is referred to as ____.

The ability to extend findings beyond experimental conditions is referred to as ____.

Dr. Engle is a toxicologist at the pharmaceutical company Pharma Giant. He wants to calculate a conservative value for his therapeutic index. Which formula should he use?

Cadence drinks caffeine every morning to help her wake up. Cadence's use of caffeine is considered instrumental because she ____.

The adequacy of controlling variables that may obscure study results and reliability is referred to as ____.

Institutional Animal Care and Use Committee (IACUC) makes ethical judgments according to its "3 R's": ____.

____ weigh the value of potential research discoveries against the potential pain and distress experienced by research animals.

In the United States, which governmental agency oversees the regulation of human research?

For the IACUC, the 3 R's address the necessity of using animals. The first "R" replacement refers to: ____.

Psychopharmacology is the study of how drugs affect mood, perception, thinking, or ____.

Medical advances rely on animal research for three major reasons: ____.

What is the purpose of performing an open-label study?

When a model appears similar to a disorder, this is referred to as ____.

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

Ghb, Inhalants, and Anesthetics

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters

If drug A has an ED₅₀ value of 12.0 mg/kg, and drug B has an ED₅₀ value of 4.0 mg/kg, what can we say about the potencies of these drugs?