Question 1

From which layer do all neurons and glia of the brain and spinal cord in a vertebrate embryo arise?

Accepted Answer

A)  Mantle zone 
B)  Intermediate zone 
C)  Ventricular zone 
D)  Marginal zone 
A)  Mantle zone 
B)  Intermediate zone 
C)  Ventricular zone 
D)  Marginal zone C

Question 2

Which term refers to the segments of hindbrain tissue separated by lineage-restriction boundaries?

Accepted Answer

A)  Rhondomeres 
B)  Rhabdomeres 
C)  Rhombomeres 
D)  Telomeres 
A)  Rhondomeres 
B)  Rhabdomeres 
C)  Rhombomeres 
D)  Telomeres C

Question 3

On the basis of our knowledge of dorso-ventral patterning of the neural tube, how would you treat cultured embryonic stem cells in order to obtain motor neurons for regenerative medicine?

Accepted Answer

A)  Sonic hedgehog + retinoic acid 
B)  Sonic hedgehog + Bone morphogenetic protein 
C)  Bone morphogenetic protein 
D)  Bone morphogenetic protein + retinoic acid 
A)  Sonic hedgehog + retinoic acid 
B)  Sonic hedgehog + Bone morphogenetic protein 
C)  Bone morphogenetic protein 
D)  Bone morphogenetic protein + retinoic acid A

Question 4

Which of the following is not true of neuroblast formation in the Drosophila embryo?

Accepted Answer

A)  Embryos that lack both Notch and Delta function do not develop neuroblasts 
B)  Initially, all cells of the proneural cluster have the potential of becoming neuroblasts 
C)  Cells in which the Notch receptor is activated become epidermal cells 
D)  Cells that are Delta-expressing cells become neuroblasts 
A)  Embryos that lack both Notch and Delta function do not develop neuroblasts 
B)  Initially, all cells of the proneural cluster have the potential of becoming neuroblasts 
C)  Cells in which the Notch receptor is activated become epidermal cells 
D)  Cells that are Delta-expressing cells become neuroblasts

Question 5

Which of the following is not true of targeting motor neurons to specific regions of the developing limb?

Accepted Answer

A)  The transcription factor, Lim1, provides motor neurons with positional identity within the spinal cord 
B)  Motor neurons are guided by chemorepellents 
C)  Motor neurons express specific receptors that guide their migration into the limb 
D)  Inverting the neural tube results in failure of motor neurons to innervate their correct muscles 
A)  The transcription factor, Lim1, provides motor neurons with positional identity within the spinal cord 
B)  Motor neurons are guided by chemorepellents 
C)  Motor neurons express specific receptors that guide their migration into the limb 
D)  Inverting the neural tube results in failure of motor neurons to innervate their correct muscles

Question 6

Which of the following functions as a local organizer to induce the development of the tectum and cerebellum in rostral and caudal postions, respectively?

Accepted Answer

A)  Zona limitans intrathalamica 
B)  Midbrain-hindbrain boundary 
C)  Anterior neural ridge 
D)  Telencephalon 
A)  Zona limitans intrathalamica 
B)  Midbrain-hindbrain boundary 
C)  Anterior neural ridge 
D)  Telencephalon

Question 7

Which of the following is not associated with neuromuscular junctions?

Accepted Answer

A)  Acetylcholine receptors 
B)  Synaptic cleft 
C)  Synaptic vesicle 
D)  Dopamine 
A)  Acetylcholine receptors 
B)  Synaptic cleft 
C)  Synaptic vesicle 
D)  Dopamine

Question 8

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of cell bodies and is referred to as gray matter?

Accepted Answer

A)  Ventricular zone 
B)  Mantle zone 
C)  Intermediate zone 
D)  Marginal zone 
A)  Ventricular zone 
B)  Mantle zone 
C)  Intermediate zone 
D)  Marginal zone

Question 9

Which of the following is true of commissural axon guidance in the neural tube?

Accepted Answer

A)  Changes in the Robo3 receptor are important for selectively preventing commissural neuron midline crossing 
B)  Netrin-1 binds to its receptor, DCC, and is a chemorepellant. 
C)  Robo1/2 is a receptor that attracts commissural neurons 
D)  Commissural neurons are allowed to cross the midline multiple times 
A)  Changes in the Robo3 receptor are important for selectively preventing commissural neuron midline crossing 
B)  Netrin-1 binds to its receptor, DCC, and is a chemorepellant. 
C)  Robo1/2 is a receptor that attracts commissural neurons 
D)  Commissural neurons are allowed to cross the midline multiple times

Question 10

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of neuronal axons and is referred to as white matter?

Accepted Answer

A)  Ventricular zone 
B)  Mantle zone 
C)  Intermediate zone 
D)  Marginal zone 
A)  Ventricular zone 
B)  Mantle zone 
C)  Intermediate zone 
D)  Marginal zone

From which layer do all neurons and glia of the brain and spinal cord in a vertebrate embryo arise?

Which term refers to the segments of hindbrain tissue separated by lineage-restriction boundaries?

On the basis of our knowledge of dorso-ventral patterning of the neural tube, how would you treat cultured embryonic stem cells in order to obtain motor neurons for regenerative medicine?

Which of the following is not true of neuroblast formation in the Drosophila embryo?

Which of the following is not true of targeting motor neurons to specific regions of the developing limb?

Which of the following functions as a local organizer to induce the development of the tectum and cerebellum in rostral and caudal postions, respectively?

Which of the following is not associated with neuromuscular junctions?

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of cell bodies and is referred to as gray matter?

Which of the following is true of commissural axon guidance in the neural tube?

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of neuronal axons and is referred to as white matter?

History and Basic Concepts

Drosophila Life Cycle and Development of the Body Plan

Vertebrate Life Cycles, Experimental Techniques Human Development

Laying Down the Vertebrate Body Plan: Xenopus and Zebrafish

Laying Down and Completing the Vertebrate Body Plan: Chick and Mouse

Morphogenesis: Change in Form in the Early Embryo

Cell Differentiation Stem Cells

Germ Cells, Fertilization Sex

Organogenesis

Growth, Post-Embryonic Development and Regeneration

Plant Life Cycle and Development

Evolution and Development

Filters

Exam 11: Development of the Nervous System

From which layer do all neurons and glia of the brain and spinal cord in a vertebrate embryo arise?

Which term refers to the segments of hindbrain tissue separated by lineage-restriction boundaries?

On the basis of our knowledge of dorso-ventral patterning of the neural tube, how would you treat cultured embryonic stem cells in order to obtain motor neurons for regenerative medicine?

Which of the following is not true of neuroblast formation in the Drosophila embryo?

Which of the following is not true of targeting motor neurons to specific regions of the developing limb?

Which of the following functions as a local organizer to induce the development of the tectum and cerebellum in rostral and caudal postions, respectively?

Which of the following is not associated with neuromuscular junctions?

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of cell bodies and is referred to as gray matter?

Which of the following is true of commissural axon guidance in the neural tube?

As new neurons migrate outward to build up concentric layers of neural tissue in the brain and spinal cord, which layer consists of neuronal axons and is referred to as white matter?

History and Basic Concepts

Drosophila Life Cycle and Development of the Body Plan

Vertebrate Life Cycles, Experimental Techniques Human Development

Laying Down the Vertebrate Body Plan: Xenopus and Zebrafish

Laying Down and Completing the Vertebrate Body Plan: Chick and Mouse

Morphogenesis: Change in Form in the Early Embryo

Cell Differentiation Stem Cells

Germ Cells, Fertilization Sex

Organogenesis

Growth, Post-Embryonic Development and Regeneration

Plant Life Cycle and Development

Evolution and Development

Filters