Exam 2: Assuring Good Measurements

Suppose a lab is validating a method using GC-MS and decide to incorporate different vendor sources of methanol in determining the normal expected variation of results. This would be expressed as part of

A laboratory receives a seizure of 592 kilogram "bricks" of white powder. All appear to be similar based on physical characteristics. The laboratory has tested many such seizures in the past months and all have been shown to be cocaine. Use the ENFSI spreadsheet to determine how many samples must be initially tested to show that 90% of the seizure contains cocaine with 95% confidence.

A contributor to an uncertainty estimate is designated as a triangular distribution. This value must be divided by the square root of 6 before being used. Why?

Which approach to estimation of uncertainty utilizes a measurement assurance sample?

A laboratory validates a method for weighing solid dose drug powders on a single balance used by 4 analysts. They establish the figures of merit shown in the portion of the uncertainty budget shown below. What is the value of the contributor for the repeatability when converted to the equivalent of one standard deviation: