Question 1

What type of anthrax is most deadly and most likely to be seen in a bioterrorism attack?

Accepted Answer

A) Gastrointestinal 
B) Inhalation 
C) Cutaneous 
D) Spinal 
A) Gastrointestinal 
B) Inhalation 
C) Cutaneous 
D) Spinal B

Question 2

Botulism toxin is a(n) _____ primarily produced by Clostridium botulinum.

Accepted Answer

A) neurotoxin 
B) mucosal toxin 
C) enterotoxin 
D) endotoxin 
A) neurotoxin 
B) mucosal toxin 
C) enterotoxin 
D) endotoxin A

Question 3

Viral hemorrhagic fevers include all the following except:

Accepted Answer

A) Ebola. 
B) Crimean-Congo. 
C) Lassa fever. 
D) black fever. 
A) Ebola. 
B) Crimean-Congo. 
C) Lassa fever. 
D) black fever. D

Question 4

What is the most common presentation for tularemia?

Accepted Answer

A) Pneumonic tularemia 
B) Ulceroglandular tularemia 
C) Bubonic tularemia 
D) Septicemic tularemia 
A) Pneumonic tularemia 
B) Ulceroglandular tularemia 
C) Bubonic tularemia 
D) Septicemic tularemia

Question 5

What organism caused the disease known as the Black Death?

Accepted Answer

A) Brucella mallei 
B) Bacillus anthracis 
C) Yersinia pestis 
D) Burkholderia cepacia 
A) Brucella mallei 
B) Bacillus anthracis 
C) Yersinia pestis 
D) Burkholderia cepacia

Question 6

What federal regulation establishes the rules of possession, use, and transfer of select agents and toxins?

Accepted Answer

A) Public Health Security and Bioterrorism Preparedness and Response Act of 2002 
B) 42 CFR 73 
C) Animal Health and Inspection Act 
D) Infectious Agent Act 
A) Public Health Security and Bioterrorism Preparedness and Response Act of 2002 
B) 42 CFR 73 
C) Animal Health and Inspection Act 
D) Infectious Agent Act

Question 7

What is characteristic of smallpox?

Accepted Answer

A) The pustules penetrate deeply into the tissue 
B) Infections also occur on the palms and the soles of the feet 
C) The synchronous progression of the lesions 
D) All of the above 
A) The pustules penetrate deeply into the tissue 
B) Infections also occur on the palms and the soles of the feet 
C) The synchronous progression of the lesions 
D) All of the above

Question 8

When should a microbiologist consider Francisella tularensis?

Accepted Answer

A) Tiny, gram-negative coccobacilli that do not grow well on chocolate or MacConkey's and are biochemically inert 
B) Tiny, gram-negative coccus that grows well on blood agar 
C) Tiny, pleomorphic, poor-staining, gram-negative coccobacilli that do not grow well, if at all on blood agar 
D) None of the above 
A) Tiny, gram-negative coccobacilli that do not grow well on chocolate or MacConkey's and are biochemically inert 
B) Tiny, gram-negative coccus that grows well on blood agar 
C) Tiny, pleomorphic, poor-staining, gram-negative coccobacilli that do not grow well, if at all on blood agar 
D) None of the above

Question 9

What organism causes glanders?

Accepted Answer

A) Francisella tularensis 
B) Brucella abortus 
C) Yersinia pestis 
D) Burkholderia mallei 
A) Francisella tularensis 
B) Brucella abortus 
C) Yersinia pestis 
D) Burkholderia mallei

Question 10

A microbiologist is looking at a sheep blood agar (SBA) plate from a patient who might have been exposed to a biological agent.The colonies that are growing on the plate are nonhemolytic, large, have a ground-glass appearance, and look like a Medusa's head.On Gram stain, the colonies are large gram-positive rods that seem to have central spores.What is the most probable organism?

Accepted Answer

A) Bacillus anthracis 
B) Brucella mallei 
C) Burkholderia cepacia 
D) Yersinia pestis 
A) Bacillus anthracis 
B) Brucella mallei 
C) Burkholderia cepacia 
D) Yersinia pestis

Question 11

What category of bioterrorism agents would have the greatest impact?

Accepted Answer

A) Category A 
B) Category B 
C) Category C 
D) Category D 
A) Category A 
B) Category B 
C) Category C 
D) Category D

Question 12

What is the specimen of choice for gastrointestinal and inhalation anthrax?

Accepted Answer

A) Sputum 
B) Vesicular fluid from lesions 
C) Spinal fluid 
D) Blood 
A) Sputum 
B) Vesicular fluid from lesions 
C) Spinal fluid 
D) Blood

Question 13

Which of these are designated as sentinel hospitals in the Laboratory Response Network (LRN)?

Accepted Answer

A) Centers for Disease Control and Prevention (CD
C)  
B) Reference laboratories 
C) State public health laboratories 
D) Community hospitals with microbiology laboratories 
A) Centers for Disease Control and Prevention (CD
C)  
B) Reference laboratories 
C) State public health laboratories 
D) Community hospitals with microbiology laboratories

Question 14

Who will be most likely to suspect a covert bioterrorism attack?

Accepted Answer

A) Firefighters and the police 
B) Microbiologists and physicians 
C) The public health department 
D) Centers for Disease Control and Prevention (CD
C)  and Homeland Security 
A) Firefighters and the police 
B) Microbiologists and physicians 
C) The public health department 
D) Centers for Disease Control and Prevention (CD
C)  and Homeland Security

Question 15

What is the role of the sentinel laboratory?

Accepted Answer

A) To rule out or refer suspicious isolates 
B) To identify suspicious isolates 
C) To act as a reference laboratory for physician office laboratories 
D) None of the above 
A) To rule out or refer suspicious isolates 
B) To identify suspicious isolates 
C) To act as a reference laboratory for physician office laboratories 
D) None of the above

Question 16

How can biological weapons enter the host?

Accepted Answer

A) Through the respiratory tract 
B) Through the gastrointestinal (GI) tract 
C) Through the mucous membranes 
D) All of the above 
A) Through the respiratory tract 
B) Through the gastrointestinal (GI) tract 
C) Through the mucous membranes 
D) All of the above

Question 17

What is ricin?

Accepted Answer

A) A potent biological toxin that disrupts native DNA strands 
B) A potent biological toxin that stops cell wall synthesis 
C) A potential biological toxin that inhibits protein synthesis 
D) All of the above 
A) A potent biological toxin that disrupts native DNA strands 
B) A potent biological toxin that stops cell wall synthesis 
C) A potential biological toxin that inhibits protein synthesis 
D) All of the above

Question 18

How is smallpox diagnosed?

Accepted Answer

A) Through a Centers for Disease Control and Prevention (CD
C)  algorithm 
B) By clinical signs 
C) Through cell culture 
D) All of the above 
A) Through a Centers for Disease Control and Prevention (CD
C)  algorithm 
B) By clinical signs 
C) Through cell culture 
D) All of the above

Question 19

All the following organizations established the Laboratory Response Network except:

Accepted Answer

A) United States Army Medical Research Institute for Infectious Diseases (USAMRII
D) . 
B) Centers for Disease Control and Prevention (CD
C) . 
C) Central Intelligence Agency (CI
A) . 
D) Federal Bureau of Investigation (FBI). 
A) United States Army Medical Research Institute for Infectious Diseases (USAMRII
D) . 
B) Centers for Disease Control and Prevention (CD
C) . 
C) Central Intelligence Agency (CI
A) . 
D) Federal Bureau of Investigation (FBI).

Question 20

All of the following are synonyms for brucellosis except _____ fever.

Accepted Answer

A) Malta 
B) undulant 
C) Gibraltar 
D) relapsing 
A) Malta 
B) undulant 
C) Gibraltar 
D) relapsing

Exam 30: Agents of Bioterror and Forensic Microbiology

What type of anthrax is most deadly and most likely to be seen in a bioterrorism attack?

Botulism toxin is a(n) _____ primarily produced by Clostridium botulinum.

Viral hemorrhagic fevers include all the following except:

What is the most common presentation for tularemia?

What organism caused the disease known as the Black Death?

What federal regulation establishes the rules of possession, use, and transfer of select agents and toxins?

What is characteristic of smallpox?

When should a microbiologist consider Francisella tularensis?

What organism causes glanders?

What category of bioterrorism agents would have the greatest impact?

What is the specimen of choice for gastrointestinal and inhalation anthrax?

Which of these are designated as sentinel hospitals in the Laboratory Response Network (LRN)?

Who will be most likely to suspect a covert bioterrorism attack?

What is the role of the sentinel laboratory?

How can biological weapons enter the host?

What is ricin?

How is smallpox diagnosed?

All the following organizations established the Laboratory Response Network except:

All of the following are synonyms for brucellosis except _____ fever.

Bacterial Cell Structure, Physiology, Metabolism, and Genetics

Host-Parasite Interaction

The Laboratory Role in Infection Control

Control of Microorganisms

Performance Improvement in the Microbiology Laboratory

Specimen Collection and Processing

Microscopic Examination of Materials From Infected Sites

Use of Colony Morphology for the Presumptive Identification of Microorganisms

Biochemical Identification of Gram-Negative Bacteria

Immunodiagnosis of Infectious Diseases

Applications of Molecular Diagnostics

Antimicrobial Agent Mechanisms of Action and Resistance

Antimicrobial Susceptibility Testing

Staphylococci

Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci

Aerobic Gram-Positive Bacilli

Neisseria Species and Moraxella Catarrhalis

Haemophilus and Other Fastidious Gram-Negative Bacilli

Enterobacteriaceae

Vibrio, Aeromonas, Plesiomonas, and Campylobacter Species

Nonfermenting and Miscellaneous Gram-Negative Bacilli

Anaerobes of Clinical Importance

The Spirochetes

Chlamydia, Rickettsia and Similar Organisms

Mycoplasma and Ureaplasma

Mycobacterium Tuberculosis and Nontuberculous Mycobacteria

Medically Significant Fungi

Diagnostic Parasitology

Clinical Virology

Biofilms: Architects of Disease

Upper and Lower Respiratory Tract Infections

Skin and Soft Tissue Infections

Gastrointestinal Infections and Food Poisoning

Infections of the Central Nervous System

Bacteremia and Sepsis

Urinary Tract Infections

Genital Infections and Sexually Transmitted Diseases

Infections in Special Populations

Zoonotic Diseases

Ocular Infections

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