Question 1

An inhibitor of succinic semialdehyde reductase would:

Accepted Answer

A)  increase the synthesis of GABA. 
B)  increase the turnover of GABA. 
C)  reduce the synthesis of GHB. 
D)  increase the synthesis of GHB. 
A)  increase the synthesis of GABA. 
B)  increase the turnover of GABA. 
C)  reduce the synthesis of GHB. 
D)  increase the synthesis of GHB.

Question 2

GBL produces full substitution for GHB in the drug discrimination procedure because GBL binds to GHB receptors.

Accepted Answer

A) True 
 B)False

Question 3

You are a pharamcologist employed by a major drug company.The company would like to see if a drug that counteracted the effects of endogenous GHB might be a novel psychostimulant drug.You've been asked to develop two pharmacological strategies on how a development program could address this request.

Accepted Answer

This could involve counteracti

Question 4

A chemical found in household products that is converted by enzymes to GHB in the body is:

Accepted Answer

A)  homovanillic acid (HV
A)  
B)  acetylcholinesterase (ACh
E)  
C)  gamma-hydroxybuyrate (GH
B)  
D)  gamma-butyrolactone (GBL) 
A)  homovanillic acid (HV
A)  
B)  acetylcholinesterase (ACh
E)  
C)  gamma-hydroxybuyrate (GH
B)  
D)  gamma-butyrolactone (GBL)

Question 5

GHB had been used by weight lifters to:

Accepted Answer

A)  enhance muscle growth. 
B)  improve sleep. 
C)  as a nutrition supplement. 
D)  to reduce muscle pain. 
A)  enhance muscle growth. 
B)  improve sleep. 
C)  as a nutrition supplement. 
D)  to reduce muscle pain.

Question 6

Why might someone trying to procure GHB seek out products with gamma-butyrolactone (GBL)?

Accepted Answer

A)  GBL has the same pharmacological effects as GHB. 
B)  When taken with GHB, GBL increases the time of onset for GHB's effects. 
C)  Mixing GBL with GHB in a drink prevents GHB from being tasted. 
D)  GHB can be synthesized from GBL, which is a legal product. 
A)  GBL has the same pharmacological effects as GHB. 
B)  When taken with GHB, GBL increases the time of onset for GHB's effects. 
C)  Mixing GBL with GHB in a drink prevents GHB from being tasted. 
D)  GHB can be synthesized from GBL, which is a legal product.

Question 7

All of the following are reasons for orally administering GHB except:

Accepted Answer

A)  GHB is a salt, which readily dissolves in a liquid, such as an alcoholic drink. 
B)  GHB absorbs easily from the gastrointestinal tract. 
C)  GHB cannot be tasted in a drink. 
D)  GHB must be co-administered in a drink with 1,4-butanediol. 
A)  GHB is a salt, which readily dissolves in a liquid, such as an alcoholic drink. 
B)  GHB absorbs easily from the gastrointestinal tract. 
C)  GHB cannot be tasted in a drink. 
D)  GHB must be co-administered in a drink with 1,4-butanediol.

Question 8

Sharing similar pharmacological actions with alcohol suggests that inhalable solvents have:

Accepted Answer

A)  hallucinogenic effects. 
B)  depressant effects. 
C)  antidepressant effects. 
D)  beneficial effects for cardiovascular functioning. 
A)  hallucinogenic effects. 
B)  depressant effects. 
C)  antidepressant effects. 
D)  beneficial effects for cardiovascular functioning.

Question 9

GHB is a neurotransmitter as well as a:

Accepted Answer

A)  hormone. 
B)  protein. 
C)  enzyme. 
D)  drug. 
A)  hormone. 
B)  protein. 
C)  enzyme. 
D)  drug.

Question 10

Sodium gammahydroxybutyrate is used for the treatment of:

Accepted Answer

A)  insomnia. 
B)  narcolepsy. 
C)  attention deficit hyperactivity disorder. 
D)  dementia. 
A)  insomnia. 
B)  narcolepsy. 
C)  attention deficit hyperactivity disorder. 
D)  dementia.

Question 11

The GHB receptor is:

Accepted Answer

A)  second messenger protein. 
B)  a single transmembrane spanning receptor. 
C)  an ionotropic receptor. 
D)  a metabotropic receptor. 
A)  second messenger protein. 
B)  a single transmembrane spanning receptor. 
C)  an ionotropic receptor. 
D)  a metabotropic receptor.

Question 12

A GABAA receptor antagonist is immediately administered to those who overdose on an inhalant.

Accepted Answer

A) True 
 B)False

Question 13

Why would GHB be added to victim's alcoholic drink?

Accepted Answer

A)  GHB counteracted alcohol's effects, leading to more alcohol consumption. 
B)  GHB strengthened the depressant effects of alcohol. 
C)  GHB made the victim feel sick, causing her to leave a club early. 
D)  GHB added stimulant effects to prevent someone from feeling tired after drinking. 
A)  GHB counteracted alcohol's effects, leading to more alcohol consumption. 
B)  GHB strengthened the depressant effects of alcohol. 
C)  GHB made the victim feel sick, causing her to leave a club early. 
D)  GHB added stimulant effects to prevent someone from feeling tired after drinking.

Question 14

The high lipid solubility of inhalants means they likely:

Accepted Answer

A)  are quickly metabolized. 
B)  have extensive nonspecific binding. 
C)  rapidly absorb. 
D)  poorly cross the blood-brain barrier. 
A)  are quickly metabolized. 
B)  have extensive nonspecific binding. 
C)  rapidly absorb. 
D)  poorly cross the blood-brain barrier.

Question 15

Based on its pharmacokinetics,GHB is difficult to detect after a sexual assault for all of the following except:

Accepted Answer

A)  sexual assault victims report too late for GHB to be detected. 
B)  GHB neurotransmitter levels interfere with tests for GHB levels. 
C)  GHB remains detectable in urine for 8-12 hours. 
D)  standard blood tests following sexual assault may not detect GHB. 
A)  sexual assault victims report too late for GHB to be detected. 
B)  GHB neurotransmitter levels interfere with tests for GHB levels. 
C)  GHB remains detectable in urine for 8-12 hours. 
D)  standard blood tests following sexual assault may not detect GHB.

Question 16

The enzyme succinic semialdehyde reductase converts succinic semialdehyde to ____________.

Accepted Answer

GHB
gamma-

Question 17

While approximately 1% report abusing GHB,this value may not reflect the amount of GHB actually used for all of the following reasons except:

Accepted Answer

A)  many law enforcement agencies report moderate to high availability of GHB. 
B)  GHB may be used for nonrecreational purposes. 
C)  Users may be using GBL instead. 
D)  GHB may be used mostly for sexual assault. 
A)  many law enforcement agencies report moderate to high availability of GHB. 
B)  GHB may be used for nonrecreational purposes. 
C)  Users may be using GBL instead. 
D)  GHB may be used mostly for sexual assault.

Question 18

The release of _____________ during sleep after using GHB made GHB an attractive substance to use by bodybuilders.

Accepted Answer

A)  oxytocin 
B)  serotonin 
C)  melatonin 
D)  human growth hormone 
A)  oxytocin 
B)  serotonin 
C)  melatonin 
D)  human growth hormone

Question 19

The primary treatment of inhalant overdose is:

Accepted Answer

A)  an antagonist for GABAA receptors. 
B)  intravenous fluids. 
C)  an antipsychotic drug. 
D)  oxygen delivery. 
A)  an antagonist for GABAA receptors. 
B)  intravenous fluids. 
C)  an antipsychotic drug. 
D)  oxygen delivery.

An inhibitor of succinic semialdehyde reductase would:

GBL produces full substitution for GHB in the drug discrimination procedure because GBL binds to GHB receptors.

You are a pharamcologist employed by a major drug company.The company would like to see if a drug that counteracted the effects of endogenous GHB might be a novel psychostimulant drug.You've been asked to develop two pharmacological strategies on how a development program could address this request.

A chemical found in household products that is converted by enzymes to GHB in the body is:

GHB had been used by weight lifters to:

Why might someone trying to procure GHB seek out products with gamma-butyrolactone (GBL)?

All of the following are reasons for orally administering GHB except:

Sharing similar pharmacological actions with alcohol suggests that inhalable solvents have:

GHB is a neurotransmitter as well as a:

Sodium gammahydroxybutyrate is used for the treatment of:

The GHB receptor is:

A GABAA receptor antagonist is immediately administered to those who overdose on an inhalant.

Why would GHB be added to victim's alcoholic drink?

The high lipid solubility of inhalants means they likely:

Based on its pharmacokinetics,GHB is difficult to detect after a sexual assault for all of the following except:

The enzyme succinic semialdehyde reductase converts succinic semialdehyde to ____________.

While approximately 1% report abusing GHB,this value may not reflect the amount of GHB actually used for all of the following reasons except:

The release of _____________ during sleep after using GHB made GHB an attractive substance to use by bodybuilders.

The primary treatment of inhalant overdose is:

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters

Exam 9: GHP and Inhalants

An inhibitor of succinic semialdehyde reductase would:

GBL produces full substitution for GHB in the drug discrimination procedure because GBL binds to GHB receptors.

A chemical found in household products that is converted by enzymes to GHB in the body is:

GHB had been used by weight lifters to:

Why might someone trying to procure GHB seek out products with gamma-butyrolactone (GBL)?

All of the following are reasons for orally administering GHB except:

Sharing similar pharmacological actions with alcohol suggests that inhalable solvents have:

GHB is a neurotransmitter as well as a:

Sodium gammahydroxybutyrate is used for the treatment of:

The GHB receptor is:

A GABAA receptor antagonist is immediately administered to those who overdose on an inhalant.

Why would GHB be added to victim's alcoholic drink?

The high lipid solubility of inhalants means they likely:

Based on its pharmacokinetics,GHB is difficult to detect after a sexual assault for all of the following except:

The enzyme succinic semialdehyde reductase converts succinic semialdehyde to ____________.

While approximately 1% report abusing GHB,this value may not reflect the amount of GHB actually used for all of the following reasons except:

The release of _____________ during sleep after using GHB made GHB an attractive substance to use by bodybuilders.

The primary treatment of inhalant overdose is:

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Properties of Drugs

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters