Question 1

The distribution phase of pharmacokinetics affects a drug's __________________,the ability of a drug to reach a site of action.

Accepted Answer

biavailability

Question 2

________________ in the blood would likely reduce the amount of drug available to act in target sites,such as the brain.

Accepted Answer

A)  Absorption 
B)  Nonspecific binding 
C)  Active transport mechanisms 
D)  Pathogens 
A)  Absorption 
B)  Nonspecific binding 
C)  Active transport mechanisms 
D)  Pathogens B

Question 3

List and describe four types of tolerance.

Accepted Answer

Pharmacokinetic: Pharmacokinetic action reduces the amount of drug reaching its site of actionPharmacodynamic: Reduced responsiveness at a drug's site of action.Behavioral: Decreased behavioral responsiveness.Conditioned: Environmental stimuli elicit physiological compensatory effects to a drug's effect.Cross-tolerance: Tolerance to other drugs in the same class.

Question 4

Phase II biotransformation occurs from catabolism by enzymes through the process of __________________ and normally occurs for metabolites produced in Phase I.

Accepted Answer

The answer of Phase II biotransformation occurs from catabolism by...

Question 5

The most important criteria below for a drug that may act in the brain is:

Accepted Answer

A)  able to alter neurotransmission. 
B)  highly potent. 
C)  administered orally. 
D)  crosses the blood-brain barrier. 
A)  able to alter neurotransmission. 
B)  highly potent. 
C)  administered orally. 
D)  crosses the blood-brain barrier.

Question 6

Applying tetrodotoxin to a neuron prevent nerve impulses from firing by:

Accepted Answer

A)  producing inhibitory postsynaptic potentials. 
B)  destroying axon terminals. 
C)  blocking sodium channels. 
D)  preventing neurotransmitter reuptake. 
A)  producing inhibitory postsynaptic potentials. 
B)  destroying axon terminals. 
C)  blocking sodium channels. 
D)  preventing neurotransmitter reuptake.

Question 7

Having a drug with a high receptor affinity suggests that:

Accepted Answer

A)  the drug will strongly activate the receptor. 
B)  the drug will outcompete drugs with lower affinities for the receptor. 
C)  the drug will strongly block the receptor. 
D)  the drug will large value for a dissociation constant. 
A)  the drug will strongly activate the receptor. 
B)  the drug will outcompete drugs with lower affinities for the receptor. 
C)  the drug will strongly block the receptor. 
D)  the drug will large value for a dissociation constant.

Question 8

If a prodrug's active metabolite produced antidepressant effects,then:

Accepted Answer

A)  the prodrug is also an antidepressant drug. 
B)  the active metabolite could be likely be directly administered as an antidepressant drug. 
C)  the prodrug had acted like a placebo. 
D)  the prodrug was unable to cross the blood-brain barrier. 
A)  the prodrug is also an antidepressant drug. 
B)  the active metabolite could be likely be directly administered as an antidepressant drug. 
C)  the prodrug had acted like a placebo. 
D)  the prodrug was unable to cross the blood-brain barrier.

Question 9

If a study participant were administered 12 μEq/L of a drug in blood and the drug had a 1 hour half-life,how much drug would remain in the body after 2 hours?

Accepted Answer

A)  3 μEq/L 
B)  0 μEq/L 
C)  6 μEq/L 
D)  2 μEq/L 
A)  3 μEq/L 
B)  0 μEq/L 
C)  6 μEq/L 
D)  2 μEq/L

Question 10

A(n)_____________ refers to a drug that fails to activate a neurotransmitter receptor.

Accepted Answer

A)  partial agonist 
B)  negative modulator 
C)  agonist 
D)  antagonist 
A)  partial agonist 
B)  negative modulator 
C)  agonist 
D)  antagonist

Question 11

The following are examples of tolerance except:

Accepted Answer

A)  a physician increased the dose of a drug because a patient became unaffected by the drug. 
B)  an individual had to increase the amount of drug taken in order to still feel a drug high. 
C)  a smoker found herself tapping her finger after smoking several cigarettes. 
D)  a regular drinker realized that he needed to drink even more alcohol than he used to in order feel a buzz. 
A)  a physician increased the dose of a drug because a patient became unaffected by the drug. 
B)  an individual had to increase the amount of drug taken in order to still feel a drug high. 
C)  a smoker found herself tapping her finger after smoking several cigarettes. 
D)  a regular drinker realized that he needed to drink even more alcohol than he used to in order feel a buzz.

Question 12

Finding that someone who was dependent on the opioid heroin required high doses of opioid replacement drug methadone would serve as an example of:

Accepted Answer

A)  behavioral tolerance. 
B)  conditioned tolerance. 
C)  cross tolerance. 
D)  pharmacodynamic tolerance. 
A)  behavioral tolerance. 
B)  conditioned tolerance. 
C)  cross tolerance. 
D)  pharmacodynamic tolerance.

Question 13

A partial agonist functionally the same as an antagonist.

Accepted Answer

A) True 
 B)False

Question 14

In order to know how long a drug's effects may last,a physician must determine a drug's:

Accepted Answer

A)  nonspecific binding rate. 
B)  elimination rate. 
C)  biotransformation rate. 
D)  ideal adminstration route. 
A)  nonspecific binding rate. 
B)  elimination rate. 
C)  biotransformation rate. 
D)  ideal adminstration route.

Question 15

A _______________ binds to the same site as a neurotransmitter,prevents a neurotransmitter from binding to the receptor,and fails to activate the receptor.

Accepted Answer

A)  competitive antagonist 
B)  noncompetitive antagonist 
C)  partial agonist 
D)  negative modulator 
A)  competitive antagonist 
B)  noncompetitive antagonist 
C)  partial agonist 
D)  negative modulator

Question 16

Certain essential amino acids that are needed for brain function but do not have properties for passive diffusion:

Accepted Answer

A)  require biotransformation before they can enter the brain. 
B)  are synthesized by neurons. 
C)  must enter the brain through active transport mechanisms. 
D)  are synthesized by glial cells. 
A)  require biotransformation before they can enter the brain. 
B)  are synthesized by neurons. 
C)  must enter the brain through active transport mechanisms. 
D)  are synthesized by glial cells.

Question 17

A(n)_____________ refers to a drug that activates a neurotransmitter receptor.

Accepted Answer

A)  antagonist 
B)  agonist 
C)  partial agonist 
D)  positive modulator 
A)  antagonist 
B)  agonist 
C)  partial agonist 
D)  positive modulator

Question 18

Drugs eliminated in half-lives follow zero-order kinetics.

Accepted Answer

A) True 
 B)False

Question 19

_____________________ is the study of neurotoxins found in our environment.

Accepted Answer

A)  Environmental neurotoxicology 
B)  Toxicology 
C)  Neurotoxicology 
D)  Environmental pharmacology 
A)  Environmental neurotoxicology 
B)  Toxicology 
C)  Neurotoxicology 
D)  Environmental pharmacology

Question 20

A method called __________________ determines the prescribing of treatments most appropriate for a patient's unique biological make-up.

Accepted Answer

personaliz

The distribution phase of pharmacokinetics affects a drug's __________________,the ability of a drug to reach a site of action.

________________ in the blood would likely reduce the amount of drug available to act in target sites,such as the brain.

List and describe four types of tolerance.

Phase II biotransformation occurs from catabolism by enzymes through the process of __________________ and normally occurs for metabolites produced in Phase I.

The most important criteria below for a drug that may act in the brain is:

Applying tetrodotoxin to a neuron prevent nerve impulses from firing by:

Having a drug with a high receptor affinity suggests that:

If a prodrug's active metabolite produced antidepressant effects,then:

If a study participant were administered 12 μEq/L of a drug in blood and the drug had a 1 hour half-life,how much drug would remain in the body after 2 hours?

A(n)_____________ refers to a drug that fails to activate a neurotransmitter receptor.

The following are examples of tolerance except:

Finding that someone who was dependent on the opioid heroin required high doses of opioid replacement drug methadone would serve as an example of:

A partial agonist functionally the same as an antagonist.

In order to know how long a drug's effects may last,a physician must determine a drug's:

A _______________ binds to the same site as a neurotransmitter,prevents a neurotransmitter from binding to the receptor,and fails to activate the receptor.

Certain essential amino acids that are needed for brain function but do not have properties for passive diffusion:

A(n)_____________ refers to a drug that activates a neurotransmitter receptor.

Drugs eliminated in half-lives follow zero-order kinetics.

_____________________ is the study of neurotoxins found in our environment.

A method called __________________ determines the prescribing of treatments most appropriate for a patient's unique biological make-up.

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters

Exam 4: Properties of Drugs

The distribution phase of pharmacokinetics affects a drug's __________________,the ability of a drug to reach a site of action.

________________ in the blood would likely reduce the amount of drug available to act in target sites,such as the brain.

List and describe four types of tolerance.

Phase II biotransformation occurs from catabolism by enzymes through the process of __________________ and normally occurs for metabolites produced in Phase I.

The most important criteria below for a drug that may act in the brain is:

Applying tetrodotoxin to a neuron prevent nerve impulses from firing by:

Having a drug with a high receptor affinity suggests that:

If a prodrug's active metabolite produced antidepressant effects,then:

If a study participant were administered 12 μEq/L of a drug in blood and the drug had a 1 hour half-life,how much drug would remain in the body after 2 hours?

A(n)_____________ refers to a drug that fails to activate a neurotransmitter receptor.

The following are examples of tolerance except:

Finding that someone who was dependent on the opioid heroin required high doses of opioid replacement drug methadone would serve as an example of:

A partial agonist functionally the same as an antagonist.

In order to know how long a drug's effects may last,a physician must determine a drug's:

A _______________ binds to the same site as a neurotransmitter,prevents a neurotransmitter from binding to the receptor,and fails to activate the receptor.

Certain essential amino acids that are needed for brain function but do not have properties for passive diffusion:

A(n)_____________ refers to a drug that activates a neurotransmitter receptor.

Drugs eliminated in half-lives follow zero-order kinetics.

_____________________ is the study of neurotoxins found in our environment.

A method called __________________ determines the prescribing of treatments most appropriate for a patient's unique biological make-up.

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters