Question 1

Since adult polycystic kidney disease (ADPKD)is a

Accepted Answer

A)  recessive trait, any individual who is heterozygous for the mutant allele will be affected. 
B)  dominant trait, any individual who is heterozygous for the mutant allele will be affected. 
C)  X-linked trait, any male who is heterozygous for the mutant allele will be affected. 
D)  recessive trait, any individual who is homozygous for the mutant allele will be affected. 
E)  X-linked trait, any female who is heterozygous for the mutant allele will be affected. 
A)  recessive trait, any individual who is heterozygous for the mutant allele will be affected. 
B)  dominant trait, any individual who is heterozygous for the mutant allele will be affected. 
C)  X-linked trait, any male who is heterozygous for the mutant allele will be affected. 
D)  recessive trait, any individual who is homozygous for the mutant allele will be affected. 
E)  X-linked trait, any female who is heterozygous for the mutant allele will be affected. B

Question 2

Which of the following situations would place a child at risk to inherit PKU from his or her parents?

Accepted Answer

A)  The father is heterozygous (normal and mutant PAH alleles); the mother is homozygous normal. 
B)  The mother is heterozygous (normal and mutant PAH alleles); the father is homozygous normal. 
C)  Both parents are heterozygous (normal and mutant PAH alleles) for the PAH gene. 
D)  The father is homozygous for the mutant PAH alleles; the mother is homozygous normal. 
E)  The mother is homozygous for the mutant PAH alleles; the father is homozygous normal. 
A)  The father is heterozygous (normal and mutant PAH alleles); the mother is homozygous normal. 
B)  The mother is heterozygous (normal and mutant PAH alleles); the father is homozygous normal. 
C)  Both parents are heterozygous (normal and mutant PAH alleles) for the PAH gene. 
D)  The father is homozygous for the mutant PAH alleles; the mother is homozygous normal. 
E)  The mother is homozygous for the mutant PAH alleles; the father is homozygous normal. C

Question 3

Currently there are no programs requiring that people be tested to see if they are carriers for a genetic disease.If this changed,would you support such a policy? Why or why not? Include arguments both for and against such a policy.

Accepted Answer

Answers will vary but should address the possibility of decreased frequencies or even complete removal of certain disease alleles from the gene pool.Answers may also discuss genetic privacy issues.

Question 4

All individuals with adult polycystic kidney disease (ADPKD)carry two copies of the mutant allele.

Accepted Answer

A) True 
 B)False

Question 5

What are the genetic and biochemical basis for PKU? What type of treatment is recommended for individuals diagnosed with the disease? Explain why mandatory screening for PKU exists in every state and is considered to be ethically appropriate,while this is not the case for screening for other genetic conditions.

Accepted Answer

The gene that causes PKU is called PAH a

Question 6

Ultrasound is a

Accepted Answer

A)  diagnostic procedure used to directly detect DNA mutations. 
B)  diagnostic procedure used to analyze family history. 
C)  noninvasive technique used to image the developing fetus. 
D)  noninvasive technique used to directly detect abnormal chromosomes. 
E)  diagnostic procedure used to detect early colon cancer. 
A)  diagnostic procedure used to directly detect DNA mutations. 
B)  diagnostic procedure used to analyze family history. 
C)  noninvasive technique used to image the developing fetus. 
D)  noninvasive technique used to directly detect abnormal chromosomes. 
E)  diagnostic procedure used to detect early colon cancer.

Question 7

This type of testing is usually used to identify individuals who will develop disorders in midlife.

Accepted Answer

A)  Presymptomatic testing 
B)  Prenatal diagnosis 
C)  Ultrasonography 
D)  Carrier testing 
E)  Amniocentesis. 
A)  Presymptomatic testing 
B)  Prenatal diagnosis 
C)  Ultrasonography 
D)  Carrier testing 
E)  Amniocentesis.

Question 8

Compare and contrast amniocentesis and chorionic villus sampling (CVS).

Accepted Answer

Amniocentesis involves a needle that is

Question 9

In 1972,Congress passed a law that established a screening program to identify carriers of sickle cell anemia.

Accepted Answer

A) True 
 B)False

Question 10

Tay-Sachs disease is a fatal ____ trait.

Accepted Answer

A)  autosomal recessive 
B)  X-linked recessive 
C)  autosomal dominant 
D)  X-linked dominant 
E)  Y-linked 
A)  autosomal recessive 
B)  X-linked recessive 
C)  autosomal dominant 
D)  X-linked dominant 
E)  Y-linked

Question 11

In the Ashkenazi Jewish ?community,Tay-Sachs screening programs are combined with counseling sessions to provide information about the risks of having an affected child.

Accepted Answer

A) True 
 B)False

Question 12

Genetic testing can determine an individual's genotype.

Accepted Answer

A) True 
 B)False

Question 13

Which of the following statements about PKU is FALSE?

Accepted Answer

A)  A mutation in the PAH gene on chromosome 12 causes PKU. 
B)  PKU is one of the few genetic conditions that has a treatment. 
C)  PKU is influenced by both genetics and the environment. 
D)  PKU is inherited as an autosomal dominant trait. 
E)  People with PKU cannot convert phenylalanine to tyrosine. 
A)  A mutation in the PAH gene on chromosome 12 causes PKU. 
B)  PKU is one of the few genetic conditions that has a treatment. 
C)  PKU is influenced by both genetics and the environment. 
D)  PKU is inherited as an autosomal dominant trait. 
E)  People with PKU cannot convert phenylalanine to tyrosine.

Question 14

MATCHING
Match the appropriate term with the description.
-Tay-Sachs

Accepted Answer

A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet 
A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet

Question 15

What are the different types of prenatal tests that can be performed to diagnose genetic disorders? Give at least one advantage and disadvantage of each method.

Accepted Answer

Ultrasound can be used to diagnose genet

Question 16

A woman with PKU becomes pregnant.During her pregnancy,she should

Accepted Answer

A)  eat and drink foods containing lots of phenylalanine. 
B)  take tyrosine supplements. 
C)  find out if her partner is a carrier. 
D)  follow a strict diet avoiding phenylalanine. 
E)  do nothing special. 
A)  eat and drink foods containing lots of phenylalanine. 
B)  take tyrosine supplements. 
C)  find out if her partner is a carrier. 
D)  follow a strict diet avoiding phenylalanine. 
E)  do nothing special.

Question 17

MATCHING
Match the appropriate term with the description.
-ADPKD

Accepted Answer

A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet 
A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet

Question 18

What is the genetic defect responsible for PKU?

Accepted Answer

A)  A mutation in the PAH gene causes the body to break down phenylalanine more rapidly than normal. 
B)  A mutation in the PAH gene inactivates the phenylalanine hydroxylase enzyme. 
C)  A mutation in the PAH gene causes the body to break down the amino acid tyrosine more rapidly than normal. 
D)  A mutation in the PAH gene causes the body to break down the amino acid tyrosine more slowly than normal. 
E)  A mutated protein causes the body to convert tyrosine into phenylalanine. 
A)  A mutation in the PAH gene causes the body to break down phenylalanine more rapidly than normal. 
B)  A mutation in the PAH gene inactivates the phenylalanine hydroxylase enzyme. 
C)  A mutation in the PAH gene causes the body to break down the amino acid tyrosine more rapidly than normal. 
D)  A mutation in the PAH gene causes the body to break down the amino acid tyrosine more slowly than normal. 
E)  A mutated protein causes the body to convert tyrosine into phenylalanine.

Question 19

Prenatal testing is usually only done to detect genetic disorders in the fetus when there is a risk of such conditions.

Accepted Answer

A) True 
 B)False

Question 20

MATCHING
Match the appropriate term with the description.
-ffDNA analysis

Accepted Answer

A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet 
A) Sonar imaging of a fetus 
B) Treatments include dialysis 
C) Carriers were prevented from joining the United State Air Force 
D) Analyzes DNA present in amniotic fluid 
E) Procedure where a needle is inserted through the abdominal and uterine wall
F)Leads to death by age 3 or 4
G)Blastomere genetic testing
H)Can be done at 8-10 weeks of pregnancy
I)Treatment involves avoiding phenylalanine in the diet

Since adult polycystic kidney disease (ADPKD)is a

Which of the following situations would place a child at risk to inherit PKU from his or her parents?

Currently there are no programs requiring that people be tested to see if they are carriers for a genetic disease.If this changed,would you support such a policy? Why or why not? Include arguments both for and against such a policy.

All individuals with adult polycystic kidney disease (ADPKD)carry two copies of the mutant allele.

Ultrasound is a

This type of testing is usually used to identify individuals who will develop disorders in midlife.

Compare and contrast amniocentesis and chorionic villus sampling (CVS).

In 1972,Congress passed a law that established a screening program to identify carriers of sickle cell anemia.

Tay-Sachs disease is a fatal ____ trait.

In the Ashkenazi Jewish ?community,Tay-Sachs screening programs are combined with counseling sessions to provide information about the risks of having an affected child.

Genetic testing can determine an individual's genotype.

Which of the following statements about PKU is FALSE?

MATCHING Match the appropriate term with the description. -Tay-Sachs

What are the different types of prenatal tests that can be performed to diagnose genetic disorders? Give at least one advantage and disadvantage of each method.

A woman with PKU becomes pregnant.During her pregnancy,she should

MATCHING Match the appropriate term with the description. -ADPKD

What is the genetic defect responsible for PKU?

Prenatal testing is usually only done to detect genetic disorders in the fetus when there is a risk of such conditions.

MATCHING Match the appropriate term with the description. -ffDNA analysis

Sex and Development

Assisted Reproductive Technology

Changes in Chromosome Number

How Genes Are Transmitted From Generation to Generation

Gene Expression and Gene Regulation

Changes in DNA: Mutations and Epigenetics

Biotechnology

DNA Forensics

Genomics

Inheritance of Complex Traits

Cancer and the Cell Cycle

Behavior

Immunogenetics

Genetics and Populations

Human Evolution

A Different World: The Past, Present, and Future of Human Genetics

Biology Basics 1-Cells and Cell Structure

Biology Basics 2-DNA and RNA

Biology Basics 3-Genes, Populations, and the Environment

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Exam 8: Genetic Testing and Prenatal Diagnosis

Since adult polycystic kidney disease (ADPKD)is a

Which of the following situations would place a child at risk to inherit PKU from his or her parents?

Currently there are no programs requiring that people be tested to see if they are carriers for a genetic disease.If this changed,would you support such a policy? Why or why not? Include arguments both for and against such a policy.

All individuals with adult polycystic kidney disease (ADPKD)carry two copies of the mutant allele.

Ultrasound is a

This type of testing is usually used to identify individuals who will develop disorders in midlife.

Compare and contrast amniocentesis and chorionic villus sampling (CVS).

In 1972,Congress passed a law that established a screening program to identify carriers of sickle cell anemia.

Tay-Sachs disease is a fatal ____ trait.

In the Ashkenazi Jewish ?community,Tay-Sachs screening programs are combined with counseling sessions to provide information about the risks of having an affected child.

Genetic testing can determine an individual's genotype.

Which of the following statements about PKU is FALSE?

MATCHING Match the appropriate term with the description. -Tay-Sachs

What are the different types of prenatal tests that can be performed to diagnose genetic disorders? Give at least one advantage and disadvantage of each method.

A woman with PKU becomes pregnant.During her pregnancy,she should

MATCHING Match the appropriate term with the description. -ADPKD

What is the genetic defect responsible for PKU?

Prenatal testing is usually only done to detect genetic disorders in the fetus when there is a risk of such conditions.

MATCHING Match the appropriate term with the description. -ffDNA analysis

Sex and Development

Assisted Reproductive Technology

Changes in Chromosome Number

How Genes Are Transmitted From Generation to Generation

Gene Expression and Gene Regulation

Changes in DNA: Mutations and Epigenetics

Biotechnology

DNA Forensics

Genomics

Inheritance of Complex Traits

Cancer and the Cell Cycle

Behavior

Immunogenetics

Genetics and Populations

Human Evolution

A Different World: The Past, Present, and Future of Human Genetics

Biology Basics 1-Cells and Cell Structure

Biology Basics 2-DNA and RNA

Biology Basics 3-Genes, Populations, and the Environment

Filters