Exam 15: Paramyxo-Viruses and Rhabdoviruses

Synthesis of mRNAs in paramyxoviruses occurs through a single-entry mechanism, which is where the RNA-dependent RNA polymerase can only start transcription from the 3' end of the genome.Which of the following is a consequence of this mechanism?

Which of the following statements about paramyxoviruses is FALSE?

Most of the genomes of the paramyxoviruses have been shown to have genomes lengths that are exact multiple of 8 nucleotides.

Describe the two models that explain how the monopartite negative-strand RNA viruses produces individual mRNAs.Which of the two models does the experimental evidence support?

Which of the following describes a major difference between the positive-strand RNA viruses and negative-strand RNA viruses?

Because measles virus can infect B and T lymphocytes, it can lead to strong immunosuppression.

The F protein of the paramyxovirus measles is responsible for both binding and fusion of the virion to the host cell.

What is the function of the neuraminidase enzyme during infection with Sendai virus, a member of the paramyxovirus family?

Which of the following proteins from paramyxovirus virions interacts with the tails of the envelope glycoproteins during assembly of virions?

There are two sequence elements at the 3' end of the genomes of paramyxoviruses that are required for mRNA transcription and genome replication.These two sequences are 78 nucleotides apart.How can the polymerase bind to both of these sequence elements at the same time?

What mechanism do the paramyxoviruses use to produce 5 different proteins from a single gene on their genome?

Which of the following conditions during infection with a paramyxovirus causes the RNA-dependent RNA polymerase to switch from start-stop transcription to production of full-length positive-strand antigenomes?

Describe two major differences between transcription and genome replication in paramyxoviruses.

How is the poly(A)tail added to the 3' ends of the mRNAs produced during infection with a paramyxovirus?

Which of the following is a difference observed between the paramyxoviruses and the rhabdoviruses?

Subacute sclerosing panencephalitis (SSPE)is a common complication of measles where the virus infects the nervous tissue immediately after causing the typical measles virus symptoms.

All of the following viruses are members of the order Mononegavirales EXCEPT….

Mutation of the RNA editing site in the genome of a paramyxovirus will have which of the following effects?

Which of the following statements about rabies is FALSE?

In the paramyxoviruses, cleavage of the F0 protein into two subunits F1 and F2 is important for which of the following?