Question 1

Predict the major product for the following reaction.

Accepted Answer

The answer of Predict the major product for the following...

Question 2

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. (CH₃)<

Question 3

Propose a stepwise synthesis for the following compound from benzene.

Accepted Answer

@#IMG-DLM&_TB4454_00

Question 4

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. CH₃CH₂Cl/AlCl₃ 2. Fu

Question 5

A nitro group ___________ the benzene ring to make it __________ reactive than benzene.

Accepted Answer

The answer of A nitro group ___________ the benzene ring...

Question 6

Cyclohexene undergoes an addition reaction with bromine, but benzene does not. Instead, benzene undergoes a substitution reaction with bromine. Explain why.

Accepted Answer

Cyclohexene has localized @#LAT-DLM& electrons, wh

Question 7

Which one of the following compounds will be most reactive towards an electrophilic aromatic bromination reaction?

Accepted Answer

A)  nitrobenzene 
B)  anisole 
C)  acetanilide 
D)  benzene 
E)  benzaldehyde 
A)  nitrobenzene 
B)  anisole 
C)  acetanilide 
D)  benzene 
E)  benzaldehyde

Question 8

Predict the major product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 9

Provide the structures of the intermediate products and final product in the following reaction sequence.

Accepted Answer

The answer of Provide the structures of the intermediate products...

Question 10

Provide the reagents necessary to prepare 1-bromo-3-isobutylbenzene from benzene.

Accepted Answer

1. @#IMG-DLM&_TB4454_00 
2. Br

Question 11

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. HNO₃/H₂SO

Question 12

Predict the major product for the following reaction.

Accepted Answer

The answer of Predict the major product for the following...

Question 13

Identify the electrophile for the Friedel-Crafts acylation of benzene.

Accepted Answer

A)  aluminum tetrachloride anion 
B)  aluminum chloride 
C)  acylium ion 
D)  carbocation 
E)  carbanion 
A)  aluminum tetrachloride anion 
B)  aluminum chloride 
C)  acylium ion 
D)  carbocation 
E)  carbanion

Question 14

Draw the major resonance contributors for the intermediate that results when p-chloronitrobenzene is treated with NaOH.

Accepted Answer

The answer of Draw the major resonance contributors for the...

Question 15

Predict the product for the following reaction.

Accepted Answer

The answer of Predict the product for the following reaction....

Question 16

Which of the following substituents will direct the incoming group to the ortho/para position during electrophilic aromatic substitution?

Accepted Answer

A)  -NO2 
B)  -CF3 
C)  -Br 
D)  -COOCH3 
E)  none of these 
A)  -NO2 
B)  -CF3 
C)  -Br 
D)  -COOCH3 
E)  none of these

Question 17

Predict the product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 18

Arrange the following compounds in order of decreasing reactivity towards electrophilic aromatic substitution.

Accepted Answer

A)  V > II > I > III > IV 
B)  II > V > III > I > IV 
C)  IV > I > III > V > II 
D)  III > II > I > IV > V 
E)  IV > V > II > I > III 
A)  V > II > I > III > IV 
B)  II > V > III > I > IV 
C)  IV > I > III > V > II 
D)  III > II > I > IV > V 
E)  IV > V > II > I > III

Question 19

Which of the following substituents will not direct the incoming group to the ortho/para position during electrophilic aromatic substitution?

Accepted Answer

A)  -CH2CH3 
B)  -CF3 
C)  -OCH3 
D)  -NHCH3 
E)  -Br 
A)  -CH2CH3 
B)  -CF3 
C)  -OCH3 
D)  -NHCH3 
E)  -Br

Question 20

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. @#IMG-DLM&_TB4454

Exam 18: Aromatic Substitution Reactions

Predict the major product for the following reaction.

Provide the reagents necessary to carry out the following conversion.

Propose a stepwise synthesis for the following compound from benzene.

Provide the reagents necessary to carry out the following conversion.

A nitro group ___________ the benzene ring to make it __________ reactive than benzene.

Cyclohexene undergoes an addition reaction with bromine, but benzene does not. Instead, benzene undergoes a substitution reaction with bromine. Explain why.

Which one of the following compounds will be most reactive towards an electrophilic aromatic bromination reaction?

Predict the major product for the following reaction.

Provide the structures of the intermediate products and final product in the following reaction sequence.

Provide the reagents necessary to prepare 1-bromo-3-isobutylbenzene from benzene.

Provide the reagents necessary to carry out the following conversion.

Predict the major product for the following reaction.

Identify the electrophile for the Friedel-Crafts acylation of benzene.

Draw the major resonance contributors for the intermediate that results when p-chloronitrobenzene is treated with NaOH.

Predict the product for the following reaction.

Which of the following substituents will direct the incoming group to the ortho/para position during electrophilic aromatic substitution?

Predict the product for the following reaction.

Arrange the following compounds in order of decreasing reactivity towards electrophilic aromatic substitution.

Which of the following substituents will not direct the incoming group to the ortho/para position during electrophilic aromatic substitution?

Provide the reagents necessary to carry out the following conversion.

A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

Molecular Representations

Acids and Bases

Alkanes and Cycloalkanes

Stereoisomerism

Chemical Reactivity and Mechanisms

Alkyl Halides: Nucleophilic Substitution and Elimination Reactions

Addition Reactions of Alkenes

Alkynes

Radical Reactions

Synthesis

Alcohols and Phenols

Ethers and Epoxides; Thiols and Sulfides

Infrared Spectroscopy and Mass Spectrometry

Nuclear Magnetic Resonance Spectroscopy

Conjugated Pi Systems and Pericyclic Reactions

Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Alpha Carbon Chemistry: Enols and Enolates

Amines

Introduction to Organometallic Compounds

Carbohydrates

Amino Acids, Peptides, and Proteins

Lipids

Synthetic Polymers

Filters

A nitro group _ the benzene ring to make it reactive than benzene.