The second messenger produced from the hydrolysis of PIP2 that activates the increase of Ca++ concentrations in the cytoplasm is:

A) diacylglycerol (DAG). B) phosphatidylinositol (PI). C) phosphatidylinositol-4,5-bisphosphate (PIP2). D) inositol-1,4,5-trisphosphate (IP3). E) inositol-1,4-bisphosphate (IP2). A) diacylglycerol (DAG). B) phosphatidylinositol (PI). C) phosphatidylinositol-4,5-bisphosphate (PIP2). D) inositol-1,4,5-trisphosphate (IP3). E) inositol-1,4-bisphosphate (IP2).

Exam 32: The Reception and Transmission of Extracellular Information

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It is believed that many general anesthetics work by prolonging the open time of GABA receptors. What type of channel does the GABA receptor mediate?

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Question 1

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The hydrolysis of PIP₂ by phospholipase C-β yields what membrane-soluble secondary messenger?

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Explain how neurons communicate at cholinergic synapses.

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In cholinergic synapses, small synaptic vesicles inside the synaptic knobs contain large amounts of acetylcholine (approximately 10,000 molecules per vesicle). When the membrane of the synaptic knob is stimulated by an arriving action potential, special voltage-gated Ca²⁺ channels open and Ca²⁺ ions stream into the synaptic knob, causing the acetylcholine-containing vesicles to attach to and fuse with the knob membrane. The vesicles open, spilling acetylcholine into the synaptic cleft. Binding of acetylcholine to specific acetylcholine receptors in the postsynaptic membrane causes opening of ion channels and the creation of a new action potential in the postsynaptic neuron.

Calcium binding proteins all possess two or more characteristic peptide domains for Ca⁺⁺ binding that consist of a short α-helix, a loop of 12 amino acids and a second α-helix (helix-loop-helix) that is called:

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Question 4

A specific GTPase-activating protein (GAP) binds to and activates:

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Question 5

Explain the effect of depolarization on voltage-gated ion channels.

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Question 6

Which of the following is true regarding the GTPase activity of Ras proteins?

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Question 7

All are enzymes in the enzyme cascade for activation of glycogen phosphorylase EXCEPT:

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Question 8

Each of the following statements is true EXCEPT:

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Question 9

In G-proteins, binding of GTP causes which of the following to occur?

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Question 10

Nitroglycerine is a potent because of the release of .

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Question 11

Botulism toxin inhibits the potentiation of nerve impulses by interfering with what aspect of acetylcholine signaling?

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Question 12

Like acetylcholine, and are excitatory, but must be removed by .

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Question 13

A muscarinic receptor is a subclass of receptor, and can be inhibited by .

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Question 14

G-proteins are involved in directly mediating the activity of the following EXCEPT:

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Question 15

Across a normal cellular membrane, the potential is maintained with a positive charge on the outside of the cell and a negative charge on the inside of the cell. Which of the following best explains the operation of the voltage sensor in the voltage-gated sodium channel?

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Question 16

Which of the following is NOT a second messenger?

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Question 17

The second messenger produced from the hydrolysis of PIP₂ that activates the increase of Ca⁺⁺ concentrations in the cytoplasm is:

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Question 18

of Tyr⁵²⁷ in the SH2 domain of protein tyrosine kinase pp60^c⁻^src tyrosine kinase activity by moving an "activation loop" the active site.

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Question 19

Cancerous tumors may develop from all of the following EXCEPT:

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Question 20

Showing 1 - 20 of 58

Exam 32: The Reception and Transmission of Extracellular Information

It is believed that many general anesthetics work by prolonging the open time of GABA receptors. What type of channel does the GABA receptor mediate?

The hydrolysis of PIP2 by phospholipase C-β yields what membrane-soluble secondary messenger?

Explain how neurons communicate at cholinergic synapses.​

Calcium binding proteins all possess two or more characteristic peptide domains for Ca++ binding that consist of a short α-helix, a loop of 12 amino acids and a second α-helix (helix-loop-helix) that is called:

A specific GTPase-activating protein (GAP) binds to and activates:

Explain the effect of depolarization on voltage-gated ion channels.​

Which of the following is true regarding the GTPase activity of Ras proteins?

All are enzymes in the enzyme cascade for activation of glycogen phosphorylase EXCEPT:

Each of the following statements is true EXCEPT:

In G-proteins, binding of GTP causes which of the following to occur?

Nitroglycerine is a potent ____ because of the release of ____.

Botulism toxin inhibits the potentiation of nerve impulses by interfering with what aspect of acetylcholine signaling?

Like acetylcholine, ____ and ____ are excitatory, but must be removed by ____.

A muscarinic receptor is a subclass of ____ receptor, and can be inhibited by ____.

G-proteins are involved in directly mediating the activity of the following EXCEPT:

Across a normal cellular membrane, the potential is maintained with a positive charge on the outside of the cell and a negative charge on the inside of the cell. Which of the following best explains the operation of the voltage sensor in the voltage-gated sodium channel?

Which of the following is NOT a second messenger?

The second messenger produced from the hydrolysis of PIP2 that activates the increase of Ca++ concentrations in the cytoplasm is:

____ of Tyr527 in the SH2 domain of protein tyrosine kinase pp60c−src ____ tyrosine kinase activity by moving an "activation loop" ____ the active site.

Cancerous tumors may develop from all of the following EXCEPT:

The Facts of Life: Chemistry Is the Logic of Biological Phenomena

Water: the Medium of Life

Thermodynamics of Biological Systems

Amino Acids and the Peptide Bond

Proteins: Their Primary Structure and Biological Functions

Proteins: Secondary, Tertiary, and Quaternary Structure

Carbohydrates and the Glycoconjugates of Cell Surfaces

Lipids

Membranes and Membrane Transport

Nucleotides and Nucleic Acids

Structure of Nucleic Acids

Recombinant Dna, Cloning, Chimeric Genes, and Synthetic Biology

Enzymeskinetics and Specificity

Mechanisms of Enzyme Action

Enzyme Regulation

Molecular Motors

Metabolism: an Overview

Glycolysis

The Tricarboxylic Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Fatty Acid Catabolism

Lipid Biosynthesis

Nitrogen Acquisition and Amino Acid Metabolism

Synthesis and Degradation of Nucleotides

Metabolic Integration and Organ Specialization

Dna Metabolism: Replication, Recombination, and Repair

Transcription and the Regulation of Gene Expression

Protein Synthesis

Completing the Protein Life Cycle: Folding, Processing, and Degradation

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The hydrolysis of PIP₂ by phospholipase C-β yields what membrane-soluble secondary messenger?

Explain how neurons communicate at cholinergic synapses.

Calcium binding proteins all possess two or more characteristic peptide domains for Ca⁺⁺ binding that consist of a short α-helix, a loop of 12 amino acids and a second α-helix (helix-loop-helix) that is called:

Explain the effect of depolarization on voltage-gated ion channels.

Nitroglycerine is a potent because of the release of .

Like acetylcholine, and are excitatory, but must be removed by .

A muscarinic receptor is a subclass of receptor, and can be inhibited by .

The second messenger produced from the hydrolysis of PIP₂ that activates the increase of Ca⁺⁺ concentrations in the cytoplasm is:

of Tyr⁵²⁷ in the SH2 domain of protein tyrosine kinase pp60^c⁻^src tyrosine kinase activity by moving an "activation loop" the active site.