Exam 26: RNA Metabolism

Name four general types of posttranscriptional processing reactions that are observed in RNA. Briefly (one sentence or less) point out an example of each type. In your example, identify the type of RNA molecule involved (tRNA, mRNA, rRNA, etc.), the type of "processing" involved, and whether the example is characteristic of eukaryotes or prokaryotes, or both. Do not describe specific genes, sequences, complicated structures, or enzymes.

What is the utility of the SELEX protocol and how does it work?

What statement is TRUE regarding synthesis of nucleic acids by E. coli RNA polymerase?

Which statement about the reverse transcriptases of retroviruses and the RNA replicases of other single-stranded RNA viruses, such as R17 and influenza virus, is CORRECT?

Which process is associated with the carboxy-terminal domain (CTD) of RNA polymerase II in eukaryotes?

Transfer RNAs have several bases in addition to the normal four found in RNA. How are these rare bases incorporated into the tRNA molecule?

Which factor is NOT involved in mRNA processing in vertebrates?

Which statement is NOT true about telomerase?

Which property does NOT apply to RNA polymerase from E. coli (core enzyme alone)?

Which statement about the synthesis of rRNA and tRNA in E. coli is TRUE?

Which statement about E. coli RNA polymerase (core enzyme) is FALSE?

The reverse transcriptase of an animal RNA virus catalyzes:

Which statement does NOT indicate how retrotransposons and retroviruses are similar to each other?

Which statement does NOT accurately describe a difference between RNA synthesis by polynucleotide phosphorylase and RNAP?

The 5'-terminal cap structure of eukaryotic mRNAs is a(n):

Which statement is FALSE regarding telomerase?

The excision (splicing) of many group I introns requires, in addition to the primary transcript RNA:

In order for RNA polymerase II to create a transcript, what is NOT necessary?

Which item(s) can be described as a ribozyme(s)?

List two main functions of the 5' cap structure. 99.4 distinct complexes bind to the carboxyl-terminal domain (CTD) of RNA polymerase II. List these complexes and state the consequences of the interaction with CTD.