Multiple Choice
Which of the following statements is NOT true of the pRb protein?
A) pRb is functionally inactive when it is hyperphosphorylated.
B) pRb is mostly unphosphorylated during the G0 phase of the cell cycle.
C) pRb is growth-promoting during early G1 phase.
D) pRb phosphorylation is initiated by D-type cyclins and CDK4/6.
E) pRb is functionally inactivated at the R point.
Correct Answer:
Verified
Correct Answer:
Verified
Q2: When a cell is at G<sub>0</sub>,pRb is<br>A)Undetectable.<br>B)Unphosphorylated.<br>C)Hypophosphorylated.<br>D)Hyperphosphorylated.<br>E)Overexpressed.
Q3: An increase in cyclin D activity may
Q4: Which of the following scenarios may contribute
Q5: Which of the following types of mutations
Q6: Which of the following types of mutations
Q8: All of the following are true of
Q9: Activation of Myc may result in all
Q10: The resting,nonproliferative phase of the cell cycle
Q11: Cyclin D/CDK4/6 complexes can be inhibited by<br>A)p27<sup>Kip1</sup>.<br>B)p15<sup>I</sup><sup>NK4B</sup>.<br>C)p57<sup>Kip2</sup>.<br>D)p21<sup>Cip1</sup>.<br>E)AP-1.
Q12: The critical decision point at which a