Multiple Choice
Which of the following types of mutations would NOT be advantageous to a cancer cell?
A) An inactivating mutation in pRb
B) An inactivating mutation in a gene controlling a DNA damage checkpoint
C) An inactivating mutation in p16INK4A
D) An inactivating mutation in cyclin D
E) An inactivating mutation in p19INK4D
Correct Answer:
Verified
Correct Answer:
Verified
Q1: pRb in cells undergoing differentiation will generally
Q2: When a cell is at G<sub>0</sub>,pRb is<br>A)Undetectable.<br>B)Unphosphorylated.<br>C)Hypophosphorylated.<br>D)Hyperphosphorylated.<br>E)Overexpressed.
Q3: An increase in cyclin D activity may
Q4: Which of the following scenarios may contribute
Q6: Which of the following types of mutations
Q7: Which of the following statements is NOT
Q8: All of the following are true of
Q9: Activation of Myc may result in all
Q10: The resting,nonproliferative phase of the cell cycle
Q11: Cyclin D/CDK4/6 complexes can be inhibited by<br>A)p27<sup>Kip1</sup>.<br>B)p15<sup>I</sup><sup>NK4B</sup>.<br>C)p57<sup>Kip2</sup>.<br>D)p21<sup>Cip1</sup>.<br>E)AP-1.