Multiple Choice
Which of the following types of mutations are MOST likely to be found in cancer cells?
A) Activating mutations in pRb
B) Mutations resulting in deregulation of the restriction point
C) Mutations resulting in enhanced restriction point regulation
D) Mutations that promote differentiation
E) C and D
Correct Answer:
Verified
Correct Answer:
Verified
Q1: pRb in cells undergoing differentiation will generally
Q2: When a cell is at G<sub>0</sub>,pRb is<br>A)Undetectable.<br>B)Unphosphorylated.<br>C)Hypophosphorylated.<br>D)Hyperphosphorylated.<br>E)Overexpressed.
Q3: An increase in cyclin D activity may
Q4: Which of the following scenarios may contribute
Q5: Which of the following types of mutations
Q7: Which of the following statements is NOT
Q8: All of the following are true of
Q9: Activation of Myc may result in all
Q10: The resting,nonproliferative phase of the cell cycle
Q11: Cyclin D/CDK4/6 complexes can be inhibited by<br>A)p27<sup>Kip1</sup>.<br>B)p15<sup>I</sup><sup>NK4B</sup>.<br>C)p57<sup>Kip2</sup>.<br>D)p21<sup>Cip1</sup>.<br>E)AP-1.