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A Patient with a Warm Autoantibody Has a Positive DAT

Question 6

Multiple Choice

A patient with a warm autoantibody has a positive DAT. The antibody screen was negative, but the eluate reacted uniformly with all normal cells and patient cells. Why was the antibody screen negative?


A) Reagent red blood cells were saturated with warm autoantibody from patient serum.
B) No alloantibodies were present.
C) The warm autoantibody has bound to patient RBCs in circulation.
D) Polyspecific AHG was used instead of monospecific IgG.

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