Which of the Following Statements About B Cell Tolerance Is

Multiple Choice

Which of the following statements about B cell tolerance is NOT true?

A) Negative signaling induced by monovalent antigens is a mechanism of central B cell tolerance.
B) Exclusion of B cells from follicles is a mechanism of peripheral B cell tolerance.
C) Functional anergy is a mechanism of peripheral B cell tolerance.
D) Receptor editing is a mechanism of central B cell tolerance.
E) Down-regulation of antigen receptor expression is a mechanism of central B cell tolerance.