Which One of the Following Is NOT a Mechanism of T

Multiple Choice

Which one of the following is NOT a mechanism of T cell tolerance?

A) Inhibition of T cell activation by interleukin-12 from regulatory T cells.
B) Apoptosis induced by Fas ligand binding to Fas.
C) Anergy induced by B7-1 or B7-2 binding to CTLA-4.
D) Anergy induced by peptide-major histocompatibility complex (MHC) binding to T cell receptors (TCRs) without B7-1 or B7-2 binding to CD28.
E) TCR-mediated up-regulation of Bim or similar pro-apoptotic proteins.