A 7-Month-Old Boy Is Evaluated in the Clinic for Recurrent

Multiple Choice

A 7-month-old boy is evaluated in the clinic for recurrent bacterial infections. His tonsils are not visible on physical examination. Serum immunoglobulin A (IgA) and IgG levels are markedly decreased, and serum IgM levels are slightly below normal. This infant should NOT be given the measles-mumps-rubella (MMR) vaccination because:

A) The vaccine would have no effect because he is not susceptible to infection with measles, mumps, or rubella.
B) The vaccine would have no effect because he cannot mount an appropriate humoral response.
C) The vaccine could be dangerous because he is predisposed to develop a type I hypersensitivity response to the MMR vaccine.
D) The vaccine could be dangerous because vaccination with MMR would put him at risk for developing a fatal infection.
E) Vaccination with MMR is not contraindicated in his case and should be performed to prevent future infection.