Which of the Following Patients Is Particularly Susceptible to Infection

Multiple Choice

Which of the following patients is particularly susceptible to infection with Streptococcus pneumoniae,an encapsulated bacterium?

A) A 23-year-old man with malaise,rash,and diffuse lymphadenopathy consistent with early infection with human immunodeficiency virus
B) A 54-year-old woman receiving local corticosteroid injections for knee pain
C) A 35-year-old man with Hodgkin's disease and a deficient delayed-type hypersensitivity (DTH) response to Candida antigen
D) A 6-year-old boy with sickle cell anemia who had a splenectomy
E) A 77-year-old woman on chronic renal dialysis and a strict low-protein diet