The Basic Idea of Using RFLPs as Markers of Genetic

Multiple Choice

The basic idea of using RFLPs as markers of genetic diseases is to

A) calculate the frequency of a RFLP allele and a disease phenotype.
B) determine that a particular locus gives restriction endonuclease digestion fragments of different sizes.
C) establish close linkage between a RFLP allele and a disease-associated allele.
D) generate a genetic map using biochemical markers, such as the presence or absence or enzyme activity, and correlate these markers with the presence or absence of a disease.