Which of the Following Is a Description Consistent with Acute

Multiple Choice

Which of the following is a description consistent with acute lymphocytic leukemia (ALL) ?

A) It is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood.
B) The bone marrow and peripheral blood are characterized by leukocytosis and a predominance of blast cells. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
C) There is failure of B cells to mature into plasma cells that synthesize immunoglobulins.
D) The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL.