Which of the Following Defines the FDA's De Minimis Rule

Multiple Choice

Which of the following defines the FDA's de minimis rule? 

A)  A requirement that the least toxic food additive be used on foods 
B)  The minimum amount of a food particle that can be detected 
C)  The minimum amount of nitrite that can be added to foods to prevent spoilage over a certain time frame 
D)  The amount of a food additive that causes no more than a one-in-a-million lifetime risk of cancer to human beings 
E)  The amount of a food additive that causes no more than a one-in-a-million risk of birth defects in human beings