Multiple Choice
CTLA-4,expressed by regulatory T cells and activated effector T cells,is crucial for self-tolerance as well as regulation of T cell responses of foreign antigens.Which of the following is a property of CTLA-4 that is important for its function?
A) CTLA-4 binds to CD28 and blocks its function.
B) CTLA-4 binds B7-1 and B7-2 with high affinity blocking their binding to CD28.
C) CTLA-4 binds class I MHC and blocks it ability to bind peptides.
D) CTLA-4 binds IL-2,preventing IL-2 binding to the IL-2 receptor.
E) CTLA-4 binds to IgG,preventing IgG biding to antigens.
Correct Answer:
Verified
Correct Answer:
Verified
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Q4: Which of the following statements about induction
Q5: For each feature of self-tolerance described in
Q6: For each feature of self-tolerance described in
Q7: For each feature of self-tolerance described in
Q8: The AIRE protein is expressed by thymic
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Q12: For each feature of self-tolerance described in
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